布托啡诺复合丙泊酚静脉麻醉用于人工流产术的临床观察

目的 探讨布托啡诺复合丙泊酚用于人工流产术的安全性及有效性.方法 拟行无痛人流术的健康早孕未育妇女200例,随机分为A、B两组各100例.A组：静注丙泊酚2.5 mg/kg;B组：静注布托啡诺10 μg/kg＋丙泊酚2.0 mg/kg;术中必要时追加丙泊酚（0.3～0.5） mg/kg.记录各组丙泊酚用药总量及麻醉相关情况.结果 B组丙泊酚用药总量明显小于A组（P 〈 0.05）;B组镇痛效果优于A组（P ＜ 0.05）,同时B组不良反应较少.结论 布托啡诺复合丙泊酚静脉麻醉用于人流术,麻醉效果优于单纯丙泊酚静脉麻醉,不良反应少,是一种安全有效的人工流产镇痛方法.

The clinical observation of butorphanol combined with propol used in intrvenous anesthesia for artificial abortion

Objective To determine the efficacy and safety of butorphanol combined with propofol for artificial abortion. Methods A total of 200 healthy early pregnancy women were divided into two groups （n = 100 each）： Group A： intravenous injection of propofol 2.5 mg/kg; group B： intravenous injection of butorphanol l0 I.Lg/kg＋propofol2.0 mg/kg; propofo （0.3~0.5） mg/kg was used in two groups when the operation was necessary. The total amount of propofol and anesthesia related situation were recorded. Results The total amount of propofol in group B was significantly less than group A（P 〈 0.05） ;Analgesic effection of group B was superior to group A （P 〈 0.05）, and there were fewer adverse re- actions in group B. Conclusion Butorphanol combined with propofol gave better analgesic effection than simple propo- fol for artificial abortion and proned to a little adverse reaction. So butorphanol combined with propofo｜ for artificial abortion is a safe and effective intrvenous anesthesia method.