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胎儿舌下腺内瘦素和瘦素受体免疫组织化学观察
引用本文:伍雪芳,吴学平,彭彦霄,王惠珠,贾雪梅.胎儿舌下腺内瘦素和瘦素受体免疫组织化学观察[J].皖南医学院学报,2004,23(2):92-94.
作者姓名:伍雪芳  吴学平  彭彦霄  王惠珠  贾雪梅
作者单位:安徽医科大学,组织学与胚胎学教研室,形态学中心实验室,安徽,合肥,230032
基金项目:安徽省教育厅自然科学基金项目 (2 0 0 1kj12 3 )
摘    要:的 观察胎儿舌下腺内瘦素和瘦素受体的表达、分布及发育规律。方法 HE和免疫组织化学SABC染色法。结果 胎儿舌下腺纹状管、小叶间导管上皮细胞呈瘦素及瘦素受体免疫反应阳性 ,免疫反应产物分布于导管上皮细胞胞质内 ,细胞核呈阴性反应。在胚胎发育的不同阶段 ,免疫反应强度亦不等。结论 胎儿舌下腺导管上皮呈瘦素和瘦素受体免疫反应阳性 ,可能与胎儿舌下腺的发育及功能活动的调节有关。

关 键 词:瘦素  瘦素受体  免疫组织化学  舌下腺  胎儿
文章编号:1002-0217(2004)02-0092-03
修稿时间:2003年11月12

Immunohistochemical observation of the leptin and its receptor in the sublingual gland of the human fetus
WU Xue-fang,WU Xue-ping,PENG Yan-xiao,WANG Hui-zhu,JIA Xue-mei.Immunohistochemical observation of the leptin and its receptor in the sublingual gland of the human fetus[J].Acta Academiae Medicinae Wannan,2004,23(2):92-94.
Authors:WU Xue-fang  WU Xue-ping  PENG Yan-xiao  WANG Hui-zhu  JIA Xue-mei
Abstract:Objective To study the expression, distribution and the development regularity of leptin and its receptor in the fetal sublingual glands. Methods HE staining and immunohistochemical SABC methods were used.Results The epithelial cells of striated and interlobular ducts showed positive immunoreacitivity of leptin and its receptor.The immunocomplexes distributed in the epithelial cytoplasm of the ducts. Nuclei showed negative. The immunoreactive intensity was unequal at the different embryonic stages of the fetus . Conclusion The laptin and its receptor of the epithelium of the sublingual gland ducts of the futus show positive immune response ,which may be involved in the development and the functional regulation of fetal sublingual gland.
Keywords:leptin  leptin receptor  immunohistochemistry  sublingual gland  fetus
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