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Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
Authors:Johanna Emgård  Hana Kammoun  Bethania García-Cassani  Julie Chesné  Sara M. Parigi  Jean-Marie Jacob  Hung-Wei Cheng  Elza Evren  Srustidhar Das  Paulo Czarnewski  Natalie Sleiers  Felipe Melo-Gonzalez  Egle Kvedaraite  Mattias Svensson  Elke Scandella  Matthew R. Hepworth  Samuel Huber  Burkhard Ludewig  Tim Willinger
Affiliation:1. Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, 141 86 Stockholm, Sweden;2. Champalimaud Research, Champalimaud Centre for the Unknown, 1400-038 Lisboa, Portugal;3. Immunology & Allergy Unit, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden;4. Unité Stroma, Inflammation & Tissue Repair, Institut Pasteur, 75724 Paris, France;5. INSERM U1224, 75724 Paris, France;6. Institute of Immunobiology, Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland;7. Manchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester M13 9PL, UK;8. I. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany;9. Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA;10. Howard Hughes Medical Institute
Abstract:
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  • Keywords:innate lymphoid cells  oxysterols  GPR183  EBI2  cell migration  colon  lymphoid tissue  inflammation
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