| 假鹰爪根化学成分的研究 |
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| 引用本文： | 廖时萱,韩公羽,张蕴茹,郑启泰,贺存恒. 假鹰爪根化学成分的研究[J]. 药学学报, 1989, 24(2): 110-113 |
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| 作者姓名： | 廖时萱 韩公羽 张蕴茹 郑启泰 贺存恒 |
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| 作者单位： | 第二军医大学药学系，第二军医大学药学系，第二军医大学药学系，中国医学科学院药物研究所，中国医学科学院药物研究所 上海 200433，上海 200433，上海 200433，北京 100050，北京 100050 |
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| 摘 要： | 假鹰爪(Desmos cochinensis Lour.)根的石油醚提取物中分得三个黄酮类化合物。其中化合物Ⅰ和Ⅱ分别鉴定为5,7-二羟基-6-甲酰基-8-甲基双氢黄酮(lawinal)和5,7-二羟基-6-甲酰基-8-甲基黄酮(isounonal)。Ⅲ为一含醛基的新化合物。根据光谱分析(紫外、红外、质谱、氢谱、碳谱、二维核磁共振异核位移相关谱及X-单晶衍射)证明其结构为4,7-二羟基-5-甲氧基-6-甲基-8-甲酰基黄烷。化合物Ⅰ和Ⅱ均属首次从该植物中分得。
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| 关 键 词： | 假鹰爪 4,7-二羟基-5-甲氧基-6甲基-8-甲酰基黄烷 二维核磁共振异核位移相关谱 X-单晶衍射 |
| 收稿时间： | 1987-08-31 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF THE ROOT OF DESMOS COCHINCHINENSIS LOUR. |
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| SX Liao,GY Han,YR Zhang,QT Zheng and CH He. STUDIES ON THE CHEMICAL CONSTITUENTS OF THE ROOT OF DESMOS COCHINCHINENSIS LOUR.[J]. Acta pharmaceutica Sinica, 1989, 24(2): 110-113 |
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| Authors: | SX Liao GY Han YR Zhang QT Zheng CH He |
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| Abstract: | Desmos cochinchinensis as a folk medicine is used for treatment of malaria in China. Pharmacological studies showed that the petroleum ether extract of the root of the plant exhibited anti-malarial activity. Three flavonoids were isolated from this extract, of which two were identified as lawinal and isounonal. Compound III is a new flavanol. On the basis of spectroscopic analyses (UV, IR, MS, 1HNMR, 13CNMR and X-RD) the structure was established as 4,7-dihydroxyl-5-methoxyl-6-methyl-8-formyl-flavan. I and II were found from this plant for the first time. |
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| Keywords: | Desmos chinensis Lour 4 7-Dlhydroxyl-5-methoxyl-6-methyl-8-formyl-flavan C-H COSY X-RD |
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