多层螺旋CT显示颈部动脉狭窄的价值

目的 评价多层螺旋CT(MSCT)显示颈部动脉狭窄的准确度.方法 选择临床可疑或诊断为短暂性脑缺血发作的29例患者行颈部动脉MSCT检查,并与导管法造影进行对照.结果 29例患者共203支颈部动脉中,导管法造影显示正常及轻度狭窄179支,MSCT对其中171支狭窄程度分级与前者一致;导管法造影显示中度及中度以上狭窄24支,MSCT对其中22支狭窄程度分级与前者一致,MSCT显示中度及中度以上狭窄的灵敏度、特异度、阳性预测值和阴性预计值分别为91.7%(22/24)、95.5%(171/179)、73.3%(22/30)和98.8%(171/173).在203支颈部动脉中,导管法造影显示正常、轻度及中度狭窄189支,MSCT对其中186支狭窄程度分级与前者一致;导管法造影显示重度狭窄及闭塞14支,MSCT对14支狭窄程度分级与前者一致,MSCT显示颈部动脉重度狭窄及闭塞的灵敏度、特异度、阳性预测值和阴性预测值分别为100.0%(14/14)、98.4%(186/189)、82.4%(14/17)和100.0%(186/186).结论 MSCT显示颈部动脉狭窄的准确度很高,可部分替代导管法造影.

Value of multi-slice CT angiography in detection of carotid artery stenosis

Objective To evaluate the accuracy of multi-slice CT(MSCT) angiography in detection of carotid artery stenosis. Methods A total of 29 consecutive patients with known or suspected carotid artery disease were studied by MSCT. The results were compared with quantitative carotid angiography.Results In the 203 carotid arteries of 29 patients, 22 of 24 carotid arteries with significant stenosis ( ≥ 30% reduction of vessel diameter) were correctly detected by MSCT,and 171 of 179 carotid arteries with normal or mild stenosis ( ＜ 30% reduction of vessel diameter) were correctly detected by MS CT. These values corresponded to sensitivity of 91.7% (22/24), specificity of 95.5% (171/179), positivè predictive value of 73.3% (22/30), and negative predictive value of 98.8% ( 171/173 ) for the detection of significant carotid artery stenosis by MSCT. In the 203 carotid arteries of 29 patients, 14 of 14 carotid arteries with high-grade stenosis were correctly detected by MSCT,and 186 of 189 carotid arteries with normal or mild stenosis were correctly detected by MSCT. These values corresponded to sensitivity of 100.0%(14/14), specificity of 98.4% (186/189), positive predictive value of 82.4% (14/17),and negative predictive value of 100.0%(186/186) for the detection of high-grade carotid arteries stenosis by MSCT. Conclusions MSCT angiography shows significant carotid artery stenosis with high accuracy. It may be used as an alternative for carotid angiography in detection of carotid artery stenosis.