神经生物支架在神经修复中的研究进展及新思路

神经损伤，包括周围神经和中枢神经的损伤造成的致残仍然是目前世界的一大难题。随着神经修复技术的发展，神经损伤修复的质量有了重大提高。利用生物支架材料（神经导管等）桥接神经损伤的断端，进而实现修复神经损伤是当前神经修复领域的一个研究热点。本文通过回顾近年关于神经生物支架的研究，从合适的支架材料、支架微结构及支架的微环境3个方面总结分析了当前神经生物支架的研究进展，提出了构建良好神经生物支架的新想法。

Advances and new ideas of neurobiology scaffold in repair of nerve injury

Nerve injury including peripheral nerve injury and central nerve injury has been a global problem. With the development of technology,many innovative approaches for nerve repair have been tested and some of the results are meaningful. It becomes a hot point that repair nerve injured by biological scaffold（nerve conduit）. This article reviewed and analyzed several kinds of biological scaffold materials and microenvironment with better effect in recent years. Some new ideas were raised from the three aspects：appropriate materials,microstructure,and bionic microenvironment. It is better to combine multiple measures and achieve the best effect. In addition,nerve scaffold have a bright future in repair of central nervous system.