| IGFBP-2与结直肠癌的研究进展 |
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| 引用本文： | 张红霞,娄长杰,山素贞. IGFBP-2与结直肠癌的研究进展[J]. 中国肿瘤, 2014, 23(2): 109-112 |
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| 作者姓名： | 张红霞 娄长杰 山素贞 |
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| 作者单位： | 哈尔滨医科大学附属肿瘤医院;哈尔滨医科大学附属肿瘤医院;哈尔滨医科大学附属肿瘤医院 |
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| 基金项目： | 黑龙江省留学归国科学基金（LC2013C27）；黑龙江省青年科学基金（QC2013C092） |
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| 摘 要： | 胰岛素样生长因子结合蛋白2（IGFBP-2）是胰岛素样生长因子系统的一员,IGFBP-2在神经胶质瘤、结直肠癌、前列腺癌、卵巢癌、乳腺癌等多种恶性肿瘤细胞株、患者血清及其肿瘤组织中均有表达或表达水平升高。大量的临床实验及流行病学研究涉及了IGFBP-2与结直肠癌之间的关系,全文就目前IGFBP-2与结直肠癌的研究进展作一综述。
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| 关 键 词： | IGFBP-2 结直肠癌 |
| 收稿时间： | 2013-07-16 |
Research Progress on IGFBP-2 in Colorectal Cancer |
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| Affiliation: | The Affiliated Tumor Hospital of Harbin Medical University |
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| Abstract: | Insulin-like growth factor binding protein 2 （IGFBP-2） is a member of tbe insulin-like growth factor system,IGFBP-2 was expressed or over expressed in cell lines of glioma,colorectal cancer,prostate cancer,ovarian cancer,breast cancer and expressed in patients＇ serum and tumor tissue. A large quantity of clinical experiments and epidemiological studies concern the relation- ship between IGFBP-2 and colorectal cancer. In this paper,the current research progress in IGF- BP-2 and colorectal cancer were reviewed. |
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| Keywords: | IGFBP-2 colorectal cancer |
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