| 庚型肝炎病毒同丙型肝炎病毒的联合感染和单独感染 |
| |
| 引用本文： | 雷金娥,李和平,钟晓红,郭清芳,王雯莉.庚型肝炎病毒同丙型肝炎病毒的联合感染和单独感染[J].临床肝胆病杂志,1998,14(4):222-224. |
| |
| 作者姓名： | 雷金娥 李和平 钟晓红 郭清芳 王雯莉 |
| |
| 作者单位： | 1. 710061,西安医科大学第一临床医学院检验科
2. 710061,西安医科大学卫生部临床检测中心 |
| |
| 摘 要： | 为了建立ＨＧＶ感染的酶免疫诊断方法，用计算机技术分析了ＨＧＶ序列，预测核心区，ＮＳ３区的抗原表位，合成了多段的ＨＧＶ核心和ＮＳ３区合成肽，通过免疫筛选试验，证实Ｃ２９，Ｃ４０和Ｎ３１０三段肽有免疫原性。用这三面肽包被酶标板，用间接免疫试验原理，建立了ＨＧＶ的ＥＩＡ检测方法。用中和抑制试验检测了该方法的特异性。使用ＨＧＶ ＥＩＡ方法检测卫生部临床检测中心提供的ＨＣＶ ＥＩＡ参比血清，发现３／９２抗－
|
| 关 键 词： | 庚型肝炎 丙型肝炎 联合感染 |
| 修稿时间： | 1997年9月22日 |
HGV Infection and Coinfection of HGV with HCV |
| |
| Institution: | (Lei Jine et al. First Teaching Hospital,Xian medical University) |
| |
| Abstract: | Some oligopeptides from HGV genome had been synthetied. C29 and C44 peptides coded in core and N310 peptides coded in NS3 of HGV were selected asimmobilizing antingen. 150Sera detected were from a panel for detecting antibody againist HCV. Antibody to HCV was detected in 3 of 92 samples with antibody to HCV and 12 of 58 without antibody to HCV. In 15 samples with antibody to HGV, only,two was detectable for HGV RNA by nest RT-PCR. The clinical significance of HGV single infection and coinfection of HGV and HCV needs to explore. |
| |
| Keywords: | HGV infection HCV |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
