| 绵毛马兜铃化学成分研究——Ⅳ.绵毛马兜铃内酯的化学结构测定 |
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| 引用本文： | 楼凤昌,丁林生,吴美玉. 绵毛马兜铃化学成分研究——Ⅳ.绵毛马兜铃内酯的化学结构测定[J]. 药学学报, 1983, 18(9): 684-688 |
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| 作者姓名： | 楼凤昌 丁林生 吴美玉 |
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| 作者单位： | 南京药学院中草药化学教研室(楼凤昌，丁林生)，江苏省化工研究所(吴美玉) |
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| 摘 要： | 从马兜铃属植物绵毛马兜铃Aristolochia mollissima Hance根茎中分得9种(Ⅰ～Ⅸ)成分,其中结晶Ⅲ为一新倍半萜内酯,用光谱法测定了化学结构,命名为绵毛马兜铃内酯Mollislactone,晶Ⅰ为尿囊素,晶Ⅱ为马兜铃内酯,晶Ⅳ为β-谷甾醇,晶Ⅸ为马兜铃酸,其余成分尚在研究中。
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| 关 键 词： | 绵毛马兜铃 绵毛马兜铃内酯 |
| 收稿时间： | 1982-09-27 |
THE CHEMICAL CONSTITUENTS OF ARISTOLOCILIA MOLLISSlMA HANCE. Ⅳ. DETERMINATION OF CHEMICAL STRUCTURE OF MOLLISLACTONE |
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| LOU Feng-chang,DING Lin-sheng and WU Mei-yu. THE CHEMICAL CONSTITUENTS OF ARISTOLOCILIA MOLLISSlMA HANCE. Ⅳ. DETERMINATION OF CHEMICAL STRUCTURE OF MOLLISLACTONE[J]. Acta pharmaceutica Sinica, 1983, 18(9): 684-688 |
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| Authors: | LOU Feng-chang DING Lin-sheng WU Mei-yu |
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| Abstract: | Nine chemical constituents (Ⅰ-Ⅸ) were separated from the ethanol extract of the root of Aristolochia mollissima Hance. One of them was found to be a new sesquiterpenoid lactone to which the name mollislactone was suggested. Its formula was identified to be C15H20O2, mp 134～135℃. The structure of mollislactone was elucidated on the basis of UV, IR, MS, NMR, 13C-NMR and 13C-PRFT-OFR spectroscopic analyses.The constituents Ⅰ, Ⅱ, Ⅳ and Ⅸ, were identified to be allantoin, aristolactone, β-sitosterol and aristolochic acid respectively. The identification of other constituents is in progress. |
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| Keywords: | Aristolochia mollissima Hance Mollislactone |
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