| 阿斯匹林、奥昔麻黄碱及两者并用对血小板聚集和血栓形成的影响 |
| |
| 引用本文： | 赵晓梅,厚华钢.阿斯匹林、奥昔麻黄碱及两者并用对血小板聚集和血栓形成的影响[J].中国药理学通报,1994,10(3):211-213. |
| |
| 作者姓名： | 赵晓梅 厚华钢 |
| |
| 作者单位： | 包头医学院心血管研究室 |
| |
| 摘 要： | 阿斯匹林与奥昔麻黄碱均抑制ＡＤＰ诱导的大鼠体内血小板聚集和实验性脑血栓形成．滞后电刺激大鼠颈动脉血栓形成时间．减少肾上腺素和胶原复合诱导剂静注所致小鼠肺血栓造成的死亡．剂量与效应相关．两者合用作用增强．
|
| 关 键 词： | 阿斯匹林，奥昔麻黄碱，血小板聚集，脑血栓，颈动脉血栓，肺血栓 |
Effects of the combination of Aspirin and Oxyfedrine on platelet aggregation and thrombogenesis |
| |
| ZHAO Xiao-Mei,HOU Hua-Gang,YANG Yu-Mei,SHI Shan.Effects of the combination of Aspirin and Oxyfedrine on platelet aggregation and thrombogenesis[J].Chinese Pharmacological Bulletin,1994,10(3):211-213. |
| |
| Authors: | ZHAO Xiao-Mei HOU Hua-Gang YANG Yu-Mei SHI Shan |
| |
| Abstract: | The effects of Aspirin(ASA),Oxyfedrine(OXY)and ASA OXY on plateletaggregation and generation of thrombosis werestudied.ASA and OXY respectively inhibitedplatelet aggregation in vivo induced by ADP andexperimenta cerebral thrombosis,and postPonedthe time of thrombosis induced by eletrical stimulation of the carotid artery in rate,also reducedthe death rate resulted from pulmonary thrombosis induced by inducer composed of collagen andepinephrine(iv)in mice.The effects Of combination of ASA and OXY markedly increased.Meanwhile,all of those effects showed good dose-dependent manner. |
| |
| Keywords: | Aspirin Oxyfedrine platelet aggregation cerebral thrombosis carotid artery thrombosis pulmanary thrombosis |
| 本文献已被 CNKI 维普 等数据库收录！ |
