马来西亚西部穿透性角膜移植术的适应证

目的:探讨马来西亚穿透性角膜移植术的适应证,并将其最主要的适应证和其它国家近期出版的数据相比较。方法:对1991/2005年15a期间在马来西亚吉隆坡马来亚大学医学中心接受穿透性角膜移植术的所有患者的医学资料进行回顾性研究。患者的性别、年龄、种族、术眼及手术适应证被纳入研究分析的范围。结果:共有105例(125眼)进行了穿透性角膜移植术的患者(男71例,女34例;中国人55例,印度人33例,马来西亚人17例;单眼85只,双眼20只)纳入本次研究。患者平均年龄51.3(13～79)a。穿透性角膜移植术的适应证由主到次分别为:人工晶状体植入术后大泡性角膜病变(28.8%),角膜疤痕(20.0%),圆锥角膜(17.6%),再移植(9.6%),角膜营养不良(8.8%),角膜穿孔(7.2%)。结论:在马来西亚穿透性角膜移植术最常见的适应证是人工晶状体植入术后大泡性角膜病变。在我们的研究中,穿透性角膜移植术的三大适应证是人工晶状体植入术后大泡性角膜病变、角膜疤痕和圆锥角膜,这与世界上很多国家都是类似的,但与一些国家适应证的发生率排序不同。

Indications for penetrating keratoplasty in west Malaysia

·AIM: To determine the indications for penetrating keratoplasty in Malaysia and to compare the leading indications with recently published data from other countries.·METHODS: A retrospective review of the medical records of all patients who underwent penetrating keratoplasty at Medical Centre, University of Malaya, Kuala Lumpur, Malaysia over a period of fifteen years (1991/2005) was done. The gender, age, race of patients, eye operated, indication for surgery were noted from the records, and analyzed.·RESULTS: A total of 125 penetrating keratoplasties were performed in 105 patients (male 71 and female 34; Chinese 55, Indians 33, and Malays 17; unilateral 85 and bilateral 20)during the study period. The mean age of patients was 51.3 years (range 13-79 years). The indications for penetrating keratoplasty were pseudophakic bullous keratopathy (28.8%),corneal scar (20.0%), keratoconus (17.6%), regrafts (9.6%),corneal dystrophies (8.8%) and corneal perforations (7.2%).·CONCLUSION: Pseudophakic bullous keratopathy is the most common indication for penetrating keratoplasty in Malaysia. The three leading indications (pseudophakic bullous keratopathy, corneal scar and keratoconus) in our study are similar to many countries in the world, but they differ in the order of frequency from some countries.