Effect of Prooxidants on the survival of rabbits exposed toStaphylococcus aureus toxic shock exotoxin and on the chemiluminescence of their whole blood cellsin vivo

The prooxidant Adriablastin (Adriamycin) is shown to prolong the survival of Chinchilla rabbits exposed to the toxic shock exotoxin produced byStaphylococcus aureus as well as to exert a marked effect on the time course of both spontaneous and opsonized zymosan-stimulated chemiluminescence by whole blood cells of these animals. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N ^o 9, pp. 258–259, September, 1995 (Presented by Yu. A. Vladimirov, Member of the Russian Academy of Medical Sciences)