Excitatory versus inhibitory impairments in insomnia patients: An ERP study |
| |
| Authors: | Aisha Cortoos Elke De Valck Nathalie Pattyn Olivier Mairesse Raymond Cluydts |
| |
| Institution: | 1. Dept. Pneumology — Sleep Unit, Universitair Ziekenhuis Brussel, Belgium;2. Vital Signs and Performance, Royal Military Academy, Belgium;3. Faculty of Medicine, Vrije Universiteit Brussel, Belgium;4. Dept. of Behavioral Sciences, Royal Military Academy, Belgium;5. Dept. Experimental and Applied Psychology, Vrije Universiteit Brussel, Belgium |
| |
| Abstract: | According to the neurocognitive perspective on insomnia, conditioned arousal results in impairment of information processing, as such interfering with normal sleep processes. In the present study, evening event-related potentials N100 and P200 were evaluated to assess hyperarousal in patients with insomnia and controls. 13 patients (mean age = 40.8) with polysomnographically verified sleep disruptions and 11 good sleepers (mean age = 45.4) were included. An auditory oddball paradigm was administered the evening of the polysomnography. N100 and P200 mean amplitudes and peak latencies at Fz and Cz were analyzed as a measure of respectively general arousability and inhibition of information processing. Patients experiencing insomnia were characterized by decreased P200 amplitudes compared to good sleepers. No significant differences were found for N100 amplitudes and latencies of both ERP waves. |
| |
| Keywords: | Insomnia Arousal Event-related potentials Inhibition Sleep |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
