Transcription factor 7-like 2 (TCF7L2) gene polymorphism rs7903146 is associated with stroke in type 2 diabetes patients with long disease duration |
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| Authors: | Hyung Jin Choi Dong-Hwa Lee Hyun Jeong Jeon Dae Soon Kim Yong Hee Lee Taekeun Oh |
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| Affiliation: | 1. Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju Si, Republic of Korea;2. Department of Biochemistry, Chungbuk National University College of Medicine, Cheongju Si, Republic of Korea |
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| Abstract: | Associations between TCF7L2 SNP and diabetic complications and diabetes-related factors were investigated. Subjects with rs7903146 variant had significantly higher prevalence of stroke (24.1% vs. 11.1%; P = 0.039) among subjects exhibiting a long disease duration (≥10 years). In conclusion, the TCF7L2 SNP variant may confer a higher risk of stroke in diabetic patients. |
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| Keywords: | SNP Complication TCF7L2 |
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