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Comparison of repaglinide and metformin versus metformin alone for type 2 diabetes: a meta-analysis of randomized controlled trials
Authors:Jinjin Yin  Houliang Deng  Shumin Qin  Waijiao Tang  Lu Zeng  Benjie Zhou
Affiliation:1. Department of Pharmacy, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, PR China;2. Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China;3. Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, PR China
Abstract:We conducted a meta-analysis to compare the efficacy and safety of repaglinide plus metformin with metformin alone on type 2 diabetes. Twenty-two studies were included in this meta-analysis. Results showed combination therapy was safe and could gain better outcomes in glycemic control. Well-designed studies are required to confirm this conclusion.
Keywords:Repaglinide   Metformin   Combination therapy   Type 2 diabetes mellitus   Meta-analysis
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