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CYFRA21—1,CEA联合测定对癌性胸水的诊断价值
引用本文:于方治 马立雄. CYFRA21—1,CEA联合测定对癌性胸水的诊断价值[J]. 实用肿瘤杂志, 1998, 13(3): 149-151,153
作者姓名:于方治 马立雄
作者单位:上海市胸科医院
摘    要:检测118例胸水CYFRA21-1和CEA浓度以及ADA活性。其中癌性不67例,结核性胸水40例,其它良性渗漏液11例。CYFRA21-1对癌胸水的敏感度为62.6%,特异度为90.2%,CEA的敏感度为55.2%,特异度为100%。联合测定CYFRA21-1和CEA对癌性胸水的敏感度可提高到85.1%,其临床应用值值得重视。

关 键 词:胸腔积液 癌性 诊断 CYFRA21-1 CEA

The combination of CYFRA21 1 and CEA assays in the diagnosis of malignant effusions
Yu Fangzhi,Ma Lixiong,Wu Jing et al. The combination of CYFRA21 1 and CEA assays in the diagnosis of malignant effusions[J]. Journal of Practical Oncology, 1998, 13(3): 149-151,153
Authors:Yu Fangzhi  Ma Lixiong  Wu Jing et al
Abstract:Pleural fluids were obtained from 67 patients with lung carcinomas,40 with tuberculosis,and 11 with benign disorders other than TB.The CYFRA21 1 was detected in 62.6% of carcinoma patients' effusions,while 5 of 40 TB specimens had an elevated CYFRA21 1 lvevl.The elevated CEA levels were found in 55.2% of the fluids from patients with carcinoma while the specificity was 100%.Using a combination of the CYFRA21 1 and CEA assays the sensitivity for malignant effusions was increased to 85.1%.It was concluded that the combination may be useful in distinguishing between malignant and benign effusions.
Keywords:CYFRA21 1 CEA lung cancer tuberculosis pleurorrhea ADA
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