| 周剂量顺铂化疗同步放疗治疗局部晚期鼻咽癌的临床研究 |
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| 引用本文： | 马建光,齐立星,郭洪涛.周剂量顺铂化疗同步放疗治疗局部晚期鼻咽癌的临床研究[J].承德医学院学报,2009,26(3):252-254. |
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| 作者姓名： | 马建光 齐立星 郭洪涛 |
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| 作者单位： | 周口市中心医院放疗科,河南周口,466000 |
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| 摘 要： | 目的:探讨周剂量顺铂化疗同步放疗治疗局部晚期鼻咽癌的疗效及毒副反应.方法:81例局部晚期鼻咽癌患者,随机分为顺铂同期放疗组(CRT组)和单纯放疗组(RT组).RT组患者仅行常规分割放疗,CRT组患者在常规分割放疗的基础上加用顺铂.观察两组患者的近期疗效、远期疗效和毒副反应.结果:CRT组患者颈部肿块残存率、3年局部复发率和远处转移率均明显低于RT组(P<0.05,P<0.01),3年和5年生存率明显高于RT组(P<0.05);鼻咽部肿块残存率、5年局部复发率和远处转移率以及毒副反应两组比较无明显差别(P>0.05).结论:周剂量顺铂化疗同步放疗治疗局部晚期鼻咽癌可提高患者的局部控制率和生存率,毒副反应患者可耐受.
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| 关 键 词： | 鼻咽癌 放射治疗 顺铂 周剂量化疗 |
CLINICAL RESEARCH OF WEEKLY DOSE DDP CHEMOTHERAPY COMBINED RADIOTHERAPY IN TREATMENT OF PARTLY ADVANCED NASOPHARYNGEAL CARCINOMA |
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| MA Jian-guang,QI Li-xing,GUO Hong-tao.CLINICAL RESEARCH OF WEEKLY DOSE DDP CHEMOTHERAPY COMBINED RADIOTHERAPY IN TREATMENT OF PARTLY ADVANCED NASOPHARYNGEAL CARCINOMA[J].Journal of Chengde Medical College,2009,26(3):252-254. |
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| Authors: | MA Jian-guang QI Li-xing GUO Hong-tao |
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| Institution: | MA Jian-guang,QI Li-xing,GUO Hong-tao(Department of Radiotherapy,Zhoukou Central Hospital,Hennan Zhoukou 466000,China) |
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| Abstract: | Objective:To investigate the therapeutic effects and side effects of weekly dose DDP chemotherapy combined radiotherapy in treatment of partly advanced nasopharyngeal carcinoma(NPC) .Methods:81 partly advanced NPC patients were randomly divided into CRT group and RT group.The patients in RT group were only administrated with conventional fractionated radiation therapy;The patients in CRT group were also administrated with weekly dose DDP besides radiation therapy.The nearly and long-term therapeutic effects... |
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| Keywords: | Nasopharyngeal carcinoma Radiotherapy DDP Weekly dose chemotherapy |
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