安徽省淮南市人群ABO及Rh血型分布调查

目的 调查安徽省淮南市人群ABO血型及Rh血型系统抗原分布状况.方法 用血型群体遗传学研究方法,选择淮南市的无偿献血者24 035名,进行ABO、Rh血型系统的表现型及基因频率分布调查分析.结果 淮南市人群ABO血型基因频率为r＞P＞q,表现型分布特征为O＞A＞B＞AB,RhD(-)频率为0.36％,与全国汉族人群RhD(-)频率0.2％～0.5％相吻合.结论 ABO、Rh血型为两个独立的血型系统,掌握其在淮南市人群中的分布规律,对临床科学用血及RhD(-)稀有血型档案库的建立,缓解医院输血缺乏状况,提高临床治疗水平,降低免疫性输血反应的发生非常重要.

Survey the population distribution of ABO and Rh blood group in Huainan city

Objective To explore the ABO blood group and Rh blood group system antigen distribution in Huainan area. Methods To investigate the Huainan area of 24 035 voluntary blord donors of the ABO and Rh blood group system phenotype and gene frequency distribution by the population genetics of the blood type. Results In the Huainan area population, the gene frequency of ABO blood type distribution was r 〉 P 〉 q, the distribution of phenotype was O 〉 A 〉 B 〉 AB,the distribution of RhD（ - ） frequency was 0.36% ,and this result was consistent with the RhD（ - ） frequency of 0.2% 0 0.5% of the Han population in the country. Conclusion ABO blood group and Rh blood group were two separate systems, control their distributed rule in the Huainan region was very important to the clinical use of blood, establishment of a repository of rare blood group of RhD （ - ） , alleviation the lack of state hospital transfusion, raising the level of clinical treatment and to the reducing the incidence of immunological transfusion reactions.