Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients |
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Authors: | I. V. Isakov L. M. Kurtasova |
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Affiliation: | (1) Krasnoyarsk State Medical Academy, Krasnoyarsk;(2) Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Krasnoyarsk |
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Abstract: | We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 12, pp. 661–663, December, 2007 |
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Keywords: | HIV infection immunophenotype CD69 antigen |
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