早期应用醒脑静注射液对脑出血患者远期康复疗效及安全性的影响分析

目的:研究分析早期应用醒脑静注射液对脑出血患者远期康复疗效及安全性的影响.方法:选取2014年7月至2015年9月脑出血患者94例.根据随机数字表法分为观察组与对照组各47例.对照组患者给予常规治疗,观察组则在对照组的基础上加用醒脑静注射液治疗.分别比较两组临床疗效,治疗后日常生活活动能力,治疗前后神经功能变化情况以及并发症发生情况.结果:观察组治疗总有效率为93.62%(44/47),显著高于对照组的78.72%(37/47),差异有统计学意义(P<0.05).治疗后观察组日常生活活动能力无障碍人数占比显著高于对照组,而重度功能障碍人数占比显著低于对照组,差异均有统计学意义(均P<0.05).治疗后两组神经功能缺损评分均显著低于治疗前,而观察组又显著低于对照组,差异均有统计学意义(均P<0.05).两组肺炎、肾功能损害以及脑水肿发生率对比均不明显,差异均无统计学意义(P>0.05).结论:早期应用醒脑静注射液治疗脑出血具有显著的临床疗效,且能改善患者日常生活活动能力以及神经功能,安全性较好.

Analysis of the Effect of Early Application of Xingnaojing Injection on Patients with Long-term Rehabilitation Efficacy and Safety of Cerebral Hemorrhage

Objective:To study the effect of early application of Xingnaojing Injection on patients with long-term rehabilitation efficacy and safety of cerebral hemorrhage. Methods:94 cases of cerebral hemorrhage patients admitted in our hospital from July 2014 to September 2015 were selected. According to the random number table method, all the patients were divided into observation group and control group, each had 47 ca-ses. The control group were given routine treatment, the observation group was treated with Xingnaojing injec-tion treatment on the basis of the control group. The clinical efficacy, activities of daily living, neurological function and complications were compared between the two groups after treatment. Results:The total effective rate of the observation group was 93.62% (44/47), which was significantly higher than 78.72% of the control group (37/47), the difference was statistically significant (P < 0.05). After treatment, the number of barrier free activities of daily living in the observation group was significantly higher than that in the control group, while the number of severe functional impairment was significantly lower than that of the control group, the differences were statistically significant ( P < 0.05) . After treatment, the neurological deficit scores of the two groups were significantly lower than before treatment, while the observation group was significantly lower than that of the control group, the differences were statistically significant (P < 0.05). There were no significant differences in the incidence of pneumonia, renal function damage and cerebral edema between the two groups, and the difference was not statistically significant ( P > 0.05) . Conclusion: Early application of Xingnaojing Injection in treatment of cerebral hemorrhage has significant clinical efficacy, and can improve the activities of daily living of patients and the nerve function, good safety.