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Norplant皮下埋植者淋巴细胞姐妹染色单体交换频率的观察
引用本文:柯致和,王佩珠,黄贻凤,解梦霞,涂知明,庞美玲. Norplant皮下埋植者淋巴细胞姐妹染色单体交换频率的观察[J]. 武汉大学学报(医学版), 1993, 0(1)
作者姓名:柯致和  王佩珠  黄贻凤  解梦霞  涂知明  庞美玲
作者单位:湖北医学院生物教研室,湖北医学院附属第二医院妇产科,湖北医学院生物教研室,湖北医学院生物教研室,湖北医学院生物教研室,湖北医学院附属第二医院 妇产科
摘    要:从细胞遗传学角度观察 Norplant 对女性皮下埋植者淋巴细胞姐妹染色单体互换(SCE)率的影响观察组27人,Norplant 埋植时间五年,对照组为6名健康女献血员.结果:观察组及对照组SCE 频率((?)±S)分别为9.80±2.33,9.05±3.81两组比较.差异无显著性(P>0.05),提示 Nor-plant 未引起妇女的遗传物质损伤,此项皮下埋植术的避孕方法适合中国妇女使用。

关 键 词:避孕药  女用/投药和剂量  避孕药  女用/副作用  染色体/生理学  植入物  人工

Study of the Effect of Norplant on Lymphocytes Sister Chronatid Exchange Frequency and Chromosome Abnormality
Ke Zhihe Wang Peizhu Huang Yefeng. Study of the Effect of Norplant on Lymphocytes Sister Chronatid Exchange Frequency and Chromosome Abnormality[J]. Medical Journal of Wuhan University, 1993, 0(1)
Authors:Ke Zhihe Wang Peizhu Huang Yefeng
Affiliation:Ke Zhihe~1 Wang Peizhu~2 Huang Yefeng1 Department of Biology,2 Department of Obstetrics and Gyecology,Second Affiliated Hospital,Hubei Medical College,Wuhan 430071,China)
Abstract:27 women used Norplant for 5 years as a experiment group and 7 persons without Norplant as a control group were studied.The frequencies of sister chromatid exchange between the experiment group (9.8±2.33) and the control group (9.05±3.81) differed no significantly (P>0.05).The results suggested that Norplant can not cause the chromosome obvious damages and may be used as a good contraceptive for married women who want to get conceived later.
Keywords:MeSH  contraceptive agents  female/AD  contraceptive agents  female/AE chromosomes/PH  implants.artificial
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