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人参皂苷对小鼠G_(422)胶质瘤免疫功能的影响
引用本文:顾立学,燕春义,罗俊生.人参皂苷对小鼠G_(422)胶质瘤免疫功能的影响[J].辽宁中医杂志,2007,34(4):523-524.
作者姓名:顾立学  燕春义  罗俊生
作者单位:1. 辽宁医学院附属第一医院,辽宁,锦州,121000
2. 辽宁医学院附属第二医院,辽宁,锦州,121000
摘    要:目的:探索人参皂苷对小鼠G422胶质瘤免疫功能的影响。方法:建立小鼠G422胶质瘤腋下肿瘤模型,将实验分为生理盐水(Saline)组、不同剂量人参皂苷组,观察肿瘤生长情况;通过荷瘤小鼠免疫器官指数测定、碳粒廓清法小鼠单核巨噬功能的测定初步评价人参皂苷对小鼠G422胶质瘤免疫功能的影响。结论:人参皂苷抑制小鼠G422胶质瘤可能与其刺激机体免疫器官,增加巨噬细胞吞噬功能有关。

关 键 词:人参皂苷  G422胶质瘤  免疫功能
文章编号:1000-1719(2007)04-0523-02
修稿时间:2007-01-12

Effection of Ginsenoside on mice G422 Glioma Immune Function
GU Li-xue,YAN Chun-yi,LUO Jun-sheng.Effection of Ginsenoside on mice G422 Glioma Immune Function[J].Liaoning Journal of Traditional Chinese Medicine,2007,34(4):523-524.
Authors:GU Li-xue  YAN Chun-yi  LUO Jun-sheng
Institution:1. The First Affiliated Hospital of Liaoning Medical College, Jinzhou 121001,Liaoning, China; 2. The Second Affiliated Hospital of Liaoning Medical College, Jinzhou 121001, Liaoning , China
Abstract:Objective:To explore the Effection of Ginsenoside(GS)on mice G422 Glioma immune function.Methods:The model of mouse with G422 Glioma was made,the experimental mice were randomly divided into normal saline group,Ginsenoside(GS)groups at varied concentrations and CTX group,Tumor growth states were observed;Effection of Ginsenoside(GS)on mice G422 Glioma immune function was evaluated by means of immune organ index and clearance rate of charcoal particles.Conclusions:Ginsenoside(GS) could effectively inhibite the growth of G422 Glioma,which was probably attributed to stimulating immune organ and increasing the ability of mice macrophage phagocyting.
Keywords:Ginsenoside(GS)  G422 Glioma  Immune function
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