北京市石景山区新发涂阳肺结核控制效果17年分析

目的评价北京市石景山区17年新发初治涂阳肺结核病例不住院下全面监督化疗的效果。方法对1985—2002年750例初治涂阳肺结核病例的治疗方案、监督化疗、痰菌阴转、1年转归等资料进行总结分析。结果1985—1989年使用12个月传统化疗方案,监督化疗率为83.7%,队列分析治愈率为84.3%。1990年以后调整为6个月短化方案,监督化疗率在95.7%以上,治愈率93.2%。结论在城区,把结核病控制工作纳入基层卫生保健,开展不住院下全面监督短程化疗,是当前结核病控制最有效的方法。

The analysis of the impact of tuberculosis control for new smear-positive pulmonary tuberculosis for 17 year in Shijingshan District in Beijing

Objective To evaluate the outcomes of new smear positive pulmonary tuberculosis patients under extensively directly observed treatment. Methods To summarize and analyze the data of 750 new smear positive pulmonary tuberculosis patients about their chemotherapy regimen,the management administration,sputum smear examination and the treatment outcome. Result During 1985—1989,the traditional 12-month regimen was used,83.7% of patients received DOT,and the cure rate was 84.3% according to cohort analysis.6-month regimen of HRZS was recommended since 1990,more than 95.7% of patients received DOTS,and the cure rate was above 93.2%. Conclusion In urban area,bringing the tuberculosis control into the primary health care,and implementing extensively directly observed treatment were the most effective measures for tuberculosis control.