| 特发性肺纤维化急性加重的诊治进展 |
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| 引用本文： | 苏瑾,代华平. 特发性肺纤维化急性加重的诊治进展[J]. 国际呼吸杂志, 2009, 29(18). DOI: 10.3760/cma.j.issn.1673-436X.2009.018.011 |
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| 作者姓名： | 苏瑾 代华平 |
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| 作者单位： | 首都医科大学附属北京朝阳医院北京呼吸疾病研究所,100020;首都医科大学附属北京朝阳医院北京呼吸疾病研究所,100020 |
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| 摘 要： | 通常认为特发性肺纤维化(1PF)为慢性进行性病程.近年来发现在没有明确诱因的情况下部分IPF患者在自然病程中可以出现急性恶化,称为IPF急性加重.其病死率很高.且临床并非少见.目前治疗IPF急性加重多采用大剂量糖皮质激素冲击治疗及强化氧疗.一些研究证实环抱素A、吡非尼酮、抗凝治疗在防治IPF急性加重方面町能有效.
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| 关 键 词： | 特发性肺纤维化 急性加重 诊断 治疗 |
Acute exacerbation of idiopathic pulmonary fibrosis: a review of current diagnosis and treatment |
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| SU Jin,DAI Hua-ping. Acute exacerbation of idiopathic pulmonary fibrosis: a review of current diagnosis and treatment[J]. International Journal of Respiration, 2009, 29(18). DOI: 10.3760/cma.j.issn.1673-436X.2009.018.011 |
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| Authors: | SU Jin DAI Hua-ping |
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| Abstract: | Idiopathic pulmonary fibrosis(lPF) has been described as a chronic progressive disease. Recent evidences have suggested that some patients may experience acute deterioration in the course of disease,which is termed acute exacerbation of IPF. Acute exacerbation of IPF is increasingly recognized as high fatality and common clinical event. Stoss therapy of large dose glucocorticosteroid and strengthening oxygen therapy are adopted in the treatment of the disease. A few studies have shown beneficial effects of cyclosporin A, pirfenidone and anticoagulant therapy in the management and prevention of acute exacerbation of IPF. |
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| Keywords: | Idiopathic pulmonary fibrosis Acute exacerbation Diagnosis Treatment |
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