| 电针对脑缺血大鼠的保护作用 |
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| 引用本文： | 罗勇,董为伟.电针对脑缺血大鼠的保护作用[J].上海针灸杂志,2001,20(6):38-40. |
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| 作者姓名： | 罗勇 董为伟 |
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| 作者单位： | 重庆医科大学附属第一医院神经内科, |
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| 基金项目： | 卫生部科研基金(941356)及重庆市中医管理局资助课题 |
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| 摘 要： | 目的：研究Wistar大鼠局灶脑缺血后电针对神经缺损评分、脑梗塞体积、 组织病理学指标的影响。方法：线栓法闭塞大鼠大脑中动脉，制备局灶脑缺血／再灌注模型。用神经病学评分、神经病理等方法检测电针“合谷”穴区对局灶脑缺血3h及再灌注3h、6h时神经缺损评分、脑梗塞体积、组织病理学指标的影响。结果：电针可缩小局灶脑梗塞体积，改善神经缺损评分、改善组织病理学指标。结论：电针可对局灶脑缺血／再灌注Wistar大鼠产生明显的脑保护作用。
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| 关 键 词： | 脑缺血 再灌注 电针 合谷穴 动物实验 保护作用 |
| 文章编号： | 1005-0957(2001)06-0038-03 |
| 修稿时间： | 2000年10月22 |
The Protective Effect of Electroacupuncture on the Ischemic Brain |
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| LUO Yong,DONG Wei wei.The Protective Effect of Electroacupuncture on the Ischemic Brain[J].Shanghai Journal of Acupuncture and Moxibustion,2001,20(6):38-40. |
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| Authors: | LUO Yong DONG Wei wei |
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| Institution: | LUO Yong,DONG Wei wei Department of neurology,the first hospital affiliated to Chongqing medical university,Chongqing 400016,China |
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| Abstract: | Purpose To investigate the influence of electroacupuncture on neural deficit score, cerebral infarct volume and histopathologic indices after focla cerebral ischemia in Wistar rats. Methods A rat model of focal cerebral ischemia/reperfusion was made by filament occlusion of the middle cerebral artery. Neuropathic scoring and a neuopathologic method were used to evaluate the influence of electroacupuncture of point Hegu(LI 4) on neural deficit score, cerebral infarct volume and histopathologic indices 3 hrs after focal cerebral ischemia and 3 hrs and 6 hrs after reperfusion. Results Electroacupuncture could reduce the volume of focal cerebral infarct and improve neural deficit score and histopathologic indices. Conclusion Electroacupuncture can produce a marked protecting effect on the brain in Wistar rats with focal cerebral ischemia/reperfusion. |
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| Keywords: | Cerebral ischemia Reperfusion Electroacupuncture Point Hegu Rat |
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