饮食因素与急性胰腺炎关系的病例-对照研究

目的　采用病例 对照研究方法探讨多种饮食因素与急性胰腺炎的关系 ,为该病防治提供科学依据。方法　 2 0 0 3年 3～ 5月发病并在省级以上医院住院的急性胰腺炎病人 10 0例纳入病例组 ,按年龄、性别配比选择该院骨科病人 10 0例纳入对照 1组 ,从社区选择健康人10 0例纳入对照 2组 ,用统一的调查表以相同的询问方式和态度进行问卷调查。对获取的资料用条件logistic回归进行单因素和多因素分析。结果　患病近一年来少动 (OR =1 35 6 6 )、肥胖 (OR =3 16 0 0 )、进餐不规律 (OR =2 95 47)、饥饿后暴饮暴食 (OR =1 96 0 3)、常吃肉 (OR=1 9333)、炒菜用动物油 (OR =1 5 6 5 2 )、用油量大 (OR =2 14 5 2 ) ,患病前两天生气 (OR =4 0 84 5 )、大量饮白酒 (OR =2 4 778)、饥饿后暴饮暴食 (OR =2 3837)、大量吃肉 (OR =2 4 12 1)与急性胰腺炎呈正相关。近一年来主食量大 (OR =0 6 72 4 )、饮牛奶或酸奶的频率高 (OR =0 715 4)用量大 (OR =0 4 313)、常吃绿叶蔬菜 (OR =0 36 0 8)和海带 (OR =0 5 92 4 ) ,患病前两天吃了绿叶蔬菜 (OR =0 32 88)与急性胰腺炎呈负相关。结论　饮食因素在急性胰腺炎的发生过程中可能起着重要作用

A case-control study on the dietary factors of patients with acute pancreatitis

OBJECTIVE: To explore association between dietary factor and acute pancreatitis (AP) so as to provide scientific basis for prevention of AP through healthful diet and life-style. METHODS: 100 AP patients were recruited from No. 1 Hospital affiliated to Sichuan University. Those participants in the control group 1 were from the same hospital, and those in the control group 2 were from a community. Controls were matched to cases for age (+/- 2.5) and sex. All of them were interviewed with uniform questionnaires. Conditional logistic regression was used for univariate and multivariate analysis. RESULTS: The statistic analysis indicated that AP was significantly associated with less physical activity (OR = 1.3566), obesity (OR = 3.1600), irregular eating (OR = 2.9547), engorgement after hunger (OR = 1.9603), oftentimes eating meat (OR = 1.9333), high animal oil consumption (OR = 1.5652). High rice and flour consumption (OR = 0.6724), Oftentimes drink milk (OR = 0.7154) and high milk consumption (OR = 0.4313), oftentimes eating laminavia lamx (OR = 0.5924) and green vegetable (OR = 0.3288) were inversely associated with AP. CONCLUSION: The study suggests that dietary factors may play an important role in AP.