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Primary signet-ring-cell carcinoma of the rectum in a 12-year-old boy
Authors:Soo-Young Yoo  Jin-Ho Lee  Kyung-Ran Park  Soon-Hee Jung
Affiliation:(1) Division of Pediatric Surgery, Department of Surgery, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, 162 Ilsan-dong, 220-701 Wonju, South Korea;(2) Department of Radiation Oncology, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, 162 Ilsan-dong, 220-701 Wonju, South Korea;(3) Department of Pathology, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, 162 Ilsan-dong, 220-701 Wonju, South Korea
Abstract:A case of primary signet-ring-cell carcinoma of the rectum is presented. Colorectal carcinoma is uncommon in childhood; moreover, the signet-ring-cell type is very rare even in adults. The clinical, pathologic, and biologic characteristics of this carcinoma are different from ordinary colorectal carcinomas. Our patient was a 12-year-old boy, the youngest with a signet-ring-cell carcinoma of the rectum in the English literature, who had a Dukes' C lesion. Pathologically, the tumor is characterized by diffuse infiltration of the bowel wall by signet-ring-cells. The prognosis is extremely poor.
Keywords:Signet-ring-cell carcinoma  Rectum  Colon  Linitis plastica
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