| 顽固性溃疡性结肠炎治疗的新方法 |
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| 引用本文： | 江学良,崔慧斐.顽固性溃疡性结肠炎治疗的新方法[J].世界华人消化杂志,2011(18). |
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| 作者姓名： | 江学良 崔慧斐 |
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| 作者单位： | 中国人民解放军济南军区总医院消化科;山东大学药学院; |
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| 基金项目： | 中国博士后科研基金资助项目,No.20070420213; 益普生腹泻基金资助项目,No.IDF-2010-01; 北京医学奖励基金会基金资助项目,No.XHYSJNJQZ-002~~ |
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| 摘 要： | 顽固性溃疡性结肠炎患者,传统治疗效果不理想,本文介绍应用干细胞治疗或者英夫利西作为过渡,加用黏膜修复药物,待病情完全缓解且可停用激素后,继续以免疫抑制剂或者氨基水杨酸类药物维持.采用这种限时加速的序贯治疗,可更快诱导缓解,并维持更长时间缓解及内镜下黏膜愈合,从而减少住院率和手术率,为难治性溃疡性结肠炎患者治疗提供新的治疗手段.
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| 关 键 词： | 溃疡性结肠炎 干细胞 激素抵抗 英夫利西 |
New treatments for refractory ulcerative colitis |
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| Xue-Liang Jiang.New treatments for refractory ulcerative colitis[J].World Chinese Journal of Digestology,2011(18). |
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| Authors: | Xue-Liang Jiang |
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| Institution: | Xue-Liang Jiang,Department of Gastroenterology,General Hospital of Jinan Military Command of Chinese PLA,Jinan 250031,Shandong Province,China Hui-Fei Cui,College of Pharmacy,Shandong University,Jinan 250014,China |
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| Abstract: | Traditional therapies have poor efficacy for hormone-dependent or-resistant ulcerative colitis.However,treatment with non-myeloablative cord blood stem cells and infliximab shows promising results in patients with refractory ulcerative colitis and represents a safe and effective approach to the management of refractory ulcerative colitis. |
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| Keywords: | Ulcerative colitis Stem cells Steroid resistance Infliximab |
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