| 青藤碱对炎症性肠病中肠道免疫炎症影响的研究进展 |
| |
| 引用本文： | 田亮,傅颖珺,谢勇. 青藤碱对炎症性肠病中肠道免疫炎症影响的研究进展[J]. 世界华人消化杂志, 2011, 0(14) |
| |
| 作者姓名： | 田亮 傅颖珺 谢勇 |
| |
| 作者单位： | 南昌大学第一附属医院消化研究所;南昌大学医学院药学系; |
| |
| 摘 要： | 炎症性肠病(IBD)患者肠道免疫炎症反应异常,影响和调控肠道免疫炎性反应是其治疗方法之一.现已证明青藤碱(SN)可以通过抑制淋巴细胞增殖,影响免疫细胞功能,减少炎症介质生成,平衡细胞因子的分泌等多个环节来抑制机体免疫炎症反应.本文从IBD免疫发病机制入手,总结了目前SN对机体免疫功能影响方面的研究进展,为寻求SN调控肠道免疫炎症来治疗IBD提供参考.
|
| 关 键 词： | 青藤碱 炎症性肠病 肠道免疫 |
Advances in understanding the effect of sinomenine on intestinal immune inflammation in inflammatory bowel disease |
| |
| Liang Tian,Yong Xie. Advances in understanding the effect of sinomenine on intestinal immune inflammation in inflammatory bowel disease[J]. World Chinese Journal of Digestology, 2011, 0(14) |
| |
| Authors: | Liang Tian Yong Xie |
| |
| Affiliation: | Liang Tian,Yong Xie,Institute of Digestive Disease,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China Liang Tian,Ying-Jun Fu,Department of Pharmacy,Medi-cal College of Nanchang University,China |
| |
| Abstract: | Intestinal immune inflammatory response is abnormal in patients with inflammatory bowel disease(IBD).Control of intestinal immune inflam-matory response represents one of the methods for treatment of IBD.It has been proved that sinomenine(SN)can inhibit lymphocyte proliferation,regulate immune cell function,reduce inflammation mediator production,modulate cytokine secretion,and thereby suppress the immune inflammatory response.This article gives an overview of the role of the immune response in the pathogen... |
| |
| Keywords: | Sinomenine Inflammatory bowel disease Intestinal immunity |
| 本文献已被 CNKI 等数据库收录！ |
|
