| DOG1、CD117和PDGFRA在胃肠道间质瘤中的表达及相关性 |
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| 引用本文： | 隋杏玲,郝旺,孙秀威. DOG1、CD117和PDGFRA在胃肠道间质瘤中的表达及相关性[J]. 世界华人消化杂志, 2011, 0(9): 912-918 |
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| 作者姓名： | 隋杏玲 郝旺 孙秀威 |
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| 作者单位： | 哈尔滨医科大学附属第三医院消化内科一病区; |
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| 摘 要： | 目的:探讨DOG1、CD117和血小板衍生生长因子受体α(PDGFRA)在胃肠道间质瘤(GISTs)诊断中的意义,并分析与其GISTs 临床病理因素和危险度的关系.方法:应用免疫组织化学Envision二步法检测63例GISTs及43例非GISTs间叶源性肿瘤患者中DOG1、CD117及PDGFRA的表达,并分析上述免...
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| 关 键 词： | 胃肠道间质瘤 DOG1 KIT蛋白 血小板衍生生长因子受体α 临床病理因素 危险度 |
Expression of DOG1,CD117 and PDGFRA in gastrointestinal stromal tumors |
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| Xing-Ling Sui,Wang Hao,Xiu-Wei Sun. Expression of DOG1,CD117 and PDGFRA in gastrointestinal stromal tumors[J]. World Chinese Journal of Digestology, 2011, 0(9): 912-918 |
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| Authors: | Xing-Ling Sui Wang Hao Xiu-Wei Sun |
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| Affiliation: | Xing-Ling Sui,Wang Hao,Xiu-Wei Sun,Department of Gastroenterology(Division I),the Third Affiliated Hospital of Harbin Medical University,Harbin 150040,Heilongjiang Province,China |
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| Abstract: | AIM:To investigate the significance of expression of discovered on GIST-1(DOG1),CD117 and platelet-derived growth factor receptor alpha(PDGFRA) in gastrointestinal stromal tumors(GISTs) by analyzing their correlation with clinicopathologic features and risk degree of GISTs.METHODS:The expression of DOG1,CD117 and PDGFRA was detected by immunohistochemistry in 63 cases of GISTs and 43 cases of non-GISTs.The correlation of expression of DOG1,CD117 and PDGFRA with clinicopathologic factors and risk degree of G... |
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| Keywords: | Gastrointestinal stromal tumor Discovered on GIST-1 Kit Platelet-derived growth factor receptor alpha Clinicopathologic features Risk degree |
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