| ANXA2、VEGF对HepG2肝癌细胞系转移的促进作用 |
| |
| 引用本文： | 曲艳红,杨家梅,樊青霞,周悦. ANXA2、VEGF对HepG2肝癌细胞系转移的促进作用[J]. 世界华人消化杂志, 2011, 0(11): 1174-1178 |
| |
| 作者姓名： | 曲艳红 杨家梅 樊青霞 周悦 |
| |
| 作者单位： | 郑州大学第二附属医院肿瘤科;郑州大学第一附属医院肿瘤科; |
| |
| 摘 要： | 目的:探讨膜联蛋白2(ANXA2)、血管内皮生长因子(VEGF)促进HepG2肝癌细胞系转移的作用.方法:应用Transwell、RT-PCR、Western blot,检测在不同5-氟尿嘧啶(5-FU)剂量(50、100、200、400 mg/L)干扰下,ANXA2、VEGF的表达及其促进HepG2肝癌细胞系转移的作...
|
| 关 键 词： | 膜联蛋白-2 血管内皮生长因子 肝细胞癌 HepG2肝癌细胞系 5-氟尿嘧啶 |
ANXA-2 and VEGF promote invasiveness of human liver cancer HepG2 cells |
| |
| Yan-Hong Qu,Jia-Mei Yang. ANXA-2 and VEGF promote invasiveness of human liver cancer HepG2 cells[J]. World Chinese Journal of Digestology, 2011, 0(11): 1174-1178 |
| |
| Authors: | Yan-Hong Qu Jia-Mei Yang |
| |
| Affiliation: | Yan-Hong Qu,Jia-Mei Yang,Department of Oncology,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,Henan Province,China Qing-Xia Fan,Yue Zhou,the First Affiliated Hospital of Zhengzhou University,Zheng-zhou 450000,China |
| |
| Abstract: | AIM:To investigate the role of annexin-2(ANXA-2)and vascular endothelial growth factor(VEGF)in promoting invasiveness of human liver cancer HepG2 cells.METHODS:After HepG2 cells were treated with different doses of 5-fluorouracil,cell invasiveness was detected by Transwell assay,and the mRNA and protein expression of ANXA-2 and VEGF was detected by RT-PCR and Western blot,respectively.RESULTS:The invasiveness of HepG2 cells decreased with the increase in the dose of 5-fluorouracil,with significant differenc... |
| |
| Keywords: | Annexin-2 Vascular endothelial growth factor Hepatocellular carcinoma HepG2 cells 5-fluorouracil |
| 本文献已被 CNKI 等数据库收录！ |
|
