| CADM1与DAL-1/4.1B在结直肠癌中的表达及临床意义 |
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| 引用本文： | 熊枝繁,丁巍. CADM1与DAL-1/4.1B在结直肠癌中的表达及临床意义[J]. 世界华人消化杂志, 2011, 0(8): 807-813 |
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| 作者姓名： | 熊枝繁 丁巍 |
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| 作者单位： | 华中科技大学同济医学院附属梨园医院消化内科; |
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| 基金项目： | 湖北省卫生厅科研基金一般基金资助项目,No.JX5B08~~ |
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| 摘 要： | 目的:研究CADM1和DAL-1/4.1B两种抑癌基因在结直肠癌中的表达并分析两者之间及其与结直肠癌各临床病理参数之间的关系,探讨CADM1和DAL-1/4.1B在结直肠癌发生发展中的作用,为结直肠癌的基因治疗提出新的思路.方法:应用免疫组织化学(SABC法)检测30例结直肠癌组织,10例结直肠腺瘤组织,30例正常结直...
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| 关 键 词： | 结直肠癌 细胞黏附分子1 肺腺癌差异表达因子4.1蛋白 免疫组织化学 肿瘤抑制基因 |
Clinical significance of CADM1 and DAL-1/4.1B expression in colorectal carcinoma |
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| Zhi-Fan Xiong,Wei Ding. Clinical significance of CADM1 and DAL-1/4.1B expression in colorectal carcinoma[J]. World Chinese Journal of Digestology, 2011, 0(8): 807-813 |
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| Authors: | Zhi-Fan Xiong Wei Ding |
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| Affiliation: | Zhi-Fan Xiong,Wei Ding,Department of Gastroenterology,Liyuan Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Hu-bei Province,China |
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| Abstract: | AIM: To investigate the clinicopathological signif icance of the expression of cell adhesion molecule 1 (CADM1) and differentially expressed in adenocarcinoma of the lung/4.1B (DAL-1/4.1B) proteins in colorectal carcinoma,colorectal adenoma and normal colorectal mucosa.METHODS: Immunohistochemical staining was performed to detect the expression of CADM1 and DAL-1/4.1B proteins in 30 colorectal carcinoma specimens,10 colorectal adenoma specimens,and 30 normal colorectal mucosal specimens.Western blot was use... |
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| Keywords: | Colorectal carcinoma Cell adhesion molecule 1 Differentially expressed in adenocar-cinoma of the lung/4.1B Immunohistochemistry Tumor suppressor gene |
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