| 氯化锶治疗转移性骨肿瘤疗效评价 |
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| 引用本文： | 陶新全,袁超,刘恒超,周翔.氯化锶治疗转移性骨肿瘤疗效评价[J].蚌埠医学院学报,2005,30(3):241-243. |
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| 作者姓名： | 陶新全 袁超 刘恒超 周翔 |
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| 作者单位： | 蚌埠医学院附属医院,核医学科,安徽,蚌埠,233004;蚌埠医学院附属医院,核医学科,安徽,蚌埠,233004;蚌埠医学院附属医院,核医学科,安徽,蚌埠,233004;蚌埠医学院附属医院,核医学科,安徽,蚌埠,233004 |
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| 摘 要： | 目的:观察氯化锶(89SrCl)治疗转移性骨肿瘤的疗效.方法:对22例骨转移性癌患者按体重静脉推注89SrCl 1.48～2.22 MBq/kg,观察患者的疼痛缓解、病灶变化及副作用,并进行影像学和血清肿瘤标志物的随访.结果:18例患者骨痛消失或减轻,骨转移癌疼痛总缓解率为81.8%,部分患者骨转移灶缩小、消失,血清肿瘤标志物和碱性磷酸酶下降.结论:89SrCl对骨转移癌疼痛有缓解作用,并可缩小病灶,副作用小.
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| 关 键 词： | 骨肿瘤 肿瘤/放射疗法 肿瘤转移 氯化锶 |
| 文章编号： | 1000-2200(2005)03-0241-03 |
| 修稿时间： | 2004年9月30日 |
Palliative effect of 89 SrCl on metastatic carcinoma of bone |
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| TAO Xin-quan,YUAN Chao,LIU Heng-chao,ZHOU Xiang.Palliative effect of 89 SrCl on metastatic carcinoma of bone[J].Journal of Bengbu Medical College,2005,30(3):241-243. |
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| Authors: | TAO Xin-quan YUAN Chao LIU Heng-chao ZHOU Xiang |
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| Abstract: | Objective:To evaluate the effect of ~(89)SrCl therapy on patients with metastatic carcinoma of bone.Methods:Twenty-two patients were treated by intravenous ~(89)SrCl at a dose of 1.48-2.22 MBq/kg.The bone-pain,lesion and the side-effect were observed.The imaging and serum tumor makers were followed up.Results:The bone-pain vanished or eased in 18 cases after the therapy.The response rate was 81.8%.The lesions became small or vanished in some patients and the serum tumor markers and alkaline phosphates(AKP) came down.Conclusions:~(89)SrCl has obvious effect on patients with metastatic carcinoma of bone and the side-effect is mild. |
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| Keywords: | bone neoplasms neoplasms/radiotherapy neoplasms melastasis ~(89)SrCl |
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