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胎儿睾丸移植治疗男性低睾酮血症的临床应用
引用本文:胡云飞,王玲珑,杨嗣星,张孝斌,刘修恒,詹炳炎.胎儿睾丸移植治疗男性低睾酮血症的临床应用[J].武汉大学学报(医学版),2002,23(4):362-363.
作者姓名:胡云飞  王玲珑  杨嗣星  张孝斌  刘修恒  詹炳炎
作者单位:武汉大学人民医院泌尿外科,武汉,430060
基金项目:湖北省教育厅资助项目(SW-97A054)
摘    要:目的:探讨胎儿睾丸移植在男性低睾酮血症治疗中的临床应用价值。方法:利用显微外科技术,以胎儿睾丸作移植体,为8例男性低睾酮血症患者施行了胎儿睾丸移植术。结果:术后5个月,8例患者的血清睾酮水平明显升高,性欲、性功能及第二性征明显改善,移植睾丸体积较术前增大。结论:胎儿睾丸移植治疗男性低睾酮血症有效,且胎儿睾丸免疫原性低,具有较高的临床应用价值。

关 键 词:睾丸  移植  低睾酮血症
修稿时间:2001年10月20

Fetal Testis Transplantation for the Treatment of Male Hypoandrogenism
Hu Yunfei,Wang Linglong,Yang Sixing,et al.Fetal Testis Transplantation for the Treatment of Male Hypoandrogenism[J].Medical Journal of Wuhan University,2002,23(4):362-363.
Authors:Hu Yunfei  Wang Linglong  Yang Sixing  
Institution:Hu Yunfei,Wang Linglong,Yang Sixing,et alDepartment of Urology,Remin Hospital,Wuhan University,Wuhan 430060,China
Abstract:Objective: To investigate the value of the clinical application of fetal testis for the treatment of male hypogonadism. Methods: We had performed the testicular transplantation to cure 8 patients suffered from hypogonadism with the fetal testis as donor tissue. Results: All patients had a significantly increased level of serum testosterone, and the male secondary sexual characteristics and the sexual desire were improved. The size of testis was larger than that before operation. Conclusion: Fetal testis transplantation is an effective method to cure male hypogonadism and has great value of clinical application for its weak immunogenicity.
Keywords:testis  transplantation  male hypoandrogenisim
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