BiPAP呼吸机治疗西宁地区COPD合并Ⅱ型呼吸衰竭疗效观察

目的 :了解BiPAP呼吸机治疗高海拔地区COPD合并Ⅱ型呼吸衰竭的疗效。方法 :1 2例COPD合并Ⅱ型呼吸衰竭患者在常规治疗基础上采用BiPAP呼吸机辅助通气作为治疗组 ,并取同期达同样标准而采用常规治疗的 1 5例COPD患者作为对照组。结果 :两组治疗后动脉血氧分压(PaO2 )都明显上升 (P <0 .0 5 ) ,但治疗组上升更高 ,治疗组血二氧化碳分压 (PaCO2 )比治疗组明显下降 ,治疗前后相差非常明显 (P <0 .0 1 ) ,对照组PaCO2 治疗前后相差不显著 (P >0 .0 5 ) ;治疗组临床症状缓解例数也明显多于对照组。结论 :用BiPAP呼吸机辅助通气 ,对高原地区COPD合并轻、中度呼吸衰竭疗效肯定 ,可降低PaCO2 ,提高PaO2 ,减轻症状 ,有利于呼吸肌疲劳的恢复 ,缩短了住院时间 ,提高了生活质量

Clinical Effects of BiPAP Ventilation on COPD Patients with Respiratory Failure in Altitude Areas

Objective: To investigate clinical effects of Bi-level positive airway pressure (BiPAP) ventilation on COPD patients with respiratory failure in Altitude Areas. Methods:The 12 patients with COPD, who were treated by BiPAP associated with the routine treatment, were as the test group; the 15 matched subjects serve das the control group only treating with routine way. The level of PaO 2 and PaCo 2 wwerew measured. Results:After BiPAP ventilation the level of PaO 2 and PaCO 2 were greatly improved in the test group ( P <0.05); in control group the PaO 2 was also increased but the PaCO 2 were not significantly changed. And their clinical symptoms were improved significantly in the test group than that in control group. Conclusion: BiPAP ventilation is beneficial to COPD patients with mild or medium respiratory failure; it can improve the PaO 2 and PaCO 2 and relieve symptom especially in respiratory muscle fatigue, and can improved quality of life.