| 妊娠期肝内胆汁郁积症患者血清甘胆酸检测的临床价值 |
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| 引用本文： | 胡金贵,苏琼,陈雪红.妊娠期肝内胆汁郁积症患者血清甘胆酸检测的临床价值[J].标记免疫分析与临床,2002,9(1):35-36. |
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| 作者姓名： | 胡金贵 苏琼 陈雪红 |
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| 作者单位： | 1. 兰州医学院第二附属医院核医学科放免检测中心,甘肃,兰州730030;2. 武警甘肃总队医院检验科,甘肃,兰州730050 |
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| 摘 要： | 妊娠期肝内胆汁郁积症(ICP)是发生于妊娠中、晚期的疾病,该病对围产儿影响较大.为进一步探讨血清甘胆酸(CG)对ICP的临床诊断价值,用放射免疫法对孕妇、ICP患者检测了血清CG值,并与丙氨酸转氨酶(ALT)和碱性磷酸酶(ALP)进行了对比分析,结果是:ICP组CG值明显高于妊娠组,差异非常显著(P＜0.01),其阳性率为100%;ICP组ALT阳性率为80%,ALP阳性率为40%.因此,血清CG是目前诊断ICP最敏感的血清学指标.
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| 关 键 词： | 甘胆酸 胆汁郁积症 妊娠 |
| 文章编号： | 1006-1703(2002)01-0035-02 |
| 修稿时间： | 2001年2月2日 |
Clinical Significance of Serum Glycochlicacid Detection in Diagnosis of Intrahepatic Cholestasis of Pregnancy |
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| HU Jin-gui,SU Qiong,CHEN Xue-hong.Clinical Significance of Serum Glycochlicacid Detection in Diagnosis of Intrahepatic Cholestasis of Pregnancy[J].Labeled Immunoassays and Clinical Medicine,2002,9(1):35-36. |
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| Authors: | HU Jin-gui SU Qiong CHEN Xue-hong |
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| Abstract: | Intrahepatic cholestasis of pregnancy(ICP) occurred in the middle and later phase of pregnancy. ICP had considerable effect on the perinatal babyies. To further study the effect of serum glycochlicacid in diagnosis of ICP, serum glycochlicacid was measured by radiolimmunoassay in normal pregnanty women and ICP pregnant women. The determination of alanine aminotransferase(ALT) and alkaline phosphatase (ALP) were taken as contrast. Serum glycochlicacid is significantly higher ( P <0.01)in ICP pregnant women than in normal pregnant women. The positive rate of serun glycochlicacid was 100%, the positive rate of ALT was 80%, the positive rate of ALP was 40%. Serum glycochlicacid is the most sensitive serologic index in diagnosis of ICP. |
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| Keywords: | Glycochlicacid Cholestasis Pregnancy |
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