| 后程加速超分割放射治疗食管癌疗效荟萃分析 |
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| 引用本文： | 邹长林,胡美龙. 后程加速超分割放射治疗食管癌疗效荟萃分析[J]. 中华放射肿瘤学杂志, 2001, 10(1): 18-20 |
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| 作者姓名： | 邹长林 胡美龙 |
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| 作者单位： | 浙江省温州医学院附属第一医院放射治疗科 |
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| 摘 要： | 目的 评价后程加速超分割放射治疗食管癌疗效。方法 对6个后程加速超分割放射治疗食管癌临床试验进行Meta分析。结果 采用固定效应模型计算，后超组1、3年生存率分别是常规组的2.39(1.58～3.62)、3.05(1.96～4.74）倍；采用随机效应模型计算，后超组1、3年生存率分别是常规组的2.43(1.54～3.82）、2.99(2.08～4.30）倍。结论 后程加速超分割放射治疗食管癌优于常规分割放射治疗，值得在临床上推广应用。
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| 关 键 词： | 食管肿瘤 放射疗法 后程加速超分割 放射治疗 |
| 修稿时间： | 2000-08-16 |
Meta-analysis of the effect of late course accelerated hyperfractionation radiotherapy for esophageal carcinoma |
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| ZOU Changlin,HU Meilong. Deptpartment of Radiation Oncology,Wenzhou Medical College First Hospital,Wenzhou ,China. Meta-analysis of the effect of late course accelerated hyperfractionation radiotherapy for esophageal carcinoma[J]. Chinese Journal of Radiation Oncology, 2001, 10(1): 18-20 |
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| Authors: | ZOU Changlin HU Meilong. Deptpartment of Radiation Oncology Wenzhou Medical College First Hospital Wenzhou China |
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| Affiliation: | ZOU Changlin,HU Meilong. Deptpartment of Radiation Oncology,Wenzhou Medical College First Hospital,Wenzhou 325000,China |
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| Abstract: | Objective To evaluate the effect of late course accelerated hyperfractionation radiotherapy(LCAHR) for esophageal carcinoma. Methods Six clinical trials on LCAHR for esophageal carcinoma were reviewed by means of Meta-analysis . Results The 1- and 3-year survival rates in the LCAHR group derived from the fixed effect model were 2.39 (1.58～3.62) and 3.05(1.96～4.74) times higher than the conventional fractionation group. With the random effect model,the 1- and 3-year survival rates in the LCAHR group were 2.43(1.54～3.82) and 2.99(2.08～4.30) times higher than the conventional fractionation group. Conclusion For esophageal carcinoma,the better outcome of LCAHR makes it advisable in extensive clinical practice. |
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| Keywords: | Esophageal neoplasms/radiotherapy Accelerated hyperfractionation Meta analysis |
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