肿瘤化疗使用植入式静脉输液港对比经外周静脉穿刺中心静脉置管临床价值的系统评价

目的：系统评价植入式静脉输液港(VPA)与经外周静脉穿刺中心静脉置管(PICC)在恶性肿瘤患者化疗中的临床价值。方法计算机检索CNKI、中国生物医学文献数据库(CBM)、万方数据库等中文数据库,检索时限均为从建库至2016年5月1日。系统评价的方法基于Cochrane系统评价原则。结果纳入6项研究,共594例患者。4个研究显示二者一次性穿刺成功率相似(81.6%~90.0%v s 77.0%~93.8%)。3个研究显示VPA留管时间显著长于PICC组。6项研究显示PICC组总体并发症发生率高于VPA组。结论与PICC相比,VPA留置时间长,并发症发生率低,在恶性肿瘤患者的化学治疗中值得推广。

A Systematic Review of Clinical Value in Cancer Patients with Chemothera-py uging Implantable Venous-access Port or Peripherally Inserted Central Catheter

Objective To evaluate clinical value of implantable venous port (VPA) and peripherally inserted central venous catheter (PICC) in cancer patients with chemotherapy. Methods Databases including CNKI, Chinese Biomedical Literature Database (CBM) and WanFang Database were searched from inception to May, 2016. The method was based on the princi-ple of Cochrane Systematic Review. Results 549 patients from 6 clinical trials were included. 4 studies reported the same results of intubation success rate for the first time (81.6%~90.0% vs 77.0%~93.8%). The piping indwelling time in VPA group was longer than that in PICC group as reported in 3 trials. 6 trials showed that the incidence of complicationswere significantly lower in VPA group. Conclusion Compared with PICC, VPA has a longer piping indwelling time, a lower inci-dence of complications, which suggests that VPA should be promoted.