羟考酮复合酮咯酸氨丁三醇在剖宫产术后镇痛中应用研究

目的：探究羟考酮复合酮咯酸氨丁三醇在剖宫产术后镇痛中应用效果。方法方便选取2015年7月-2016年7月于该院进行分娩的92例产妇,采用随机数字表法均分为两组。对照组采用酮咯酸氨丁三醇术后镇痛,观察组采用羟考酮复合酮咯酸氨丁三醇术后镇痛。采用疼痛视觉模拟(VAS)评分量表、舒适度(BCS)评分量表分别对两组术后疼痛及术后舒适度进行评估,进而分析羟考酮复合酮咯酸氨丁三醇在剖宫产术后镇痛中应用效果。结果随着术后镇痛时间的延长,两组产妇VAS呈降低趋势,BCS呈增高趋势,术后24 h与术后6 h相比差异有统计学意义(P<0.05)；观察组VAS评分为术后6 h(2.41±0.65)分、术后12 h(2.03±0.71)分、术后24 h(1.94±0.64)分低于对照组(3.32±0.85)分、(2.77±0.75)分、(2.38±0.69)分,BCS(2.23±0.84)分、(2.35±0.74)分、(2.54±0.55)分高于对照组(1.76±0.82)分、(1.89±0.78)分、(2.31±0.51)分,组间差异均有统计学意义(P<0.05)。两组总不良反应发生率比较差异无统计学意义(P>0.05)。结论羟考酮复合酮咯酸氨丁三醇应用于剖宫产术后镇痛效果显著,可有效降低产妇术后VAS评分、提高产妇术后舒适度；且安全可靠。

Study on Application of Oxycodone Compound Ketorolac Tromethamine in Cesarean Section Postoperative Analgesia

Objective To explore application effect of oxycodone compound ketorolac tromethamine in cesarean section postoperative analgesia.Methods Convenient selection 92 parturient women delivered in our hospital from July 2015 to July 2016 were divided by random number table into two groups equally. The control group received ketorolac tromethamine postoperative analgesia, the observation group received oxycodone compound ketorolac tromethamine postoperative analgesi-a. Pain visual analogue (VAS) score scale, comfort (BCS) rating scale were used to evaluate postoperative pain and postoper-ative comfort in the two groups, application effect of oxycodone compound ketorolac tromethamine in cesarean section post-operative analgesia was analyzed.Results With extending of postoperative analgesia time, VAS of the two groups were de-creased, BCS were increased, there was a significant difference at postoperative 24 h and postoperative 6 h (P<0.05); VAS scores of the observation group were postoperative 6 h (2.41±0.65)score, postoperative 12 h (2.03±0.71)score, postoperative 24 h (1.94 ±0.64)score, which were significantly lower than the control group (3.32 ±0.85)score, (2.77 ±0.75)score, (2.38 ± 0.69)score], BCS (2.23 ±0.84)score, (2.35 ±0.74)score, (2.54 ±0.55)score were significantly higher than the control group (1.76±0.82)score, (1.89±0.78)score, (2.31±0.51)score] (P<0.05). There was no significant difference in the incidence of ad-verse reactions between the two groups (P>0.05). Conclusion Effect of oxycodone compound ketorolac tromethamine in ce-sarean section postoperative analgesia is remarkable, can reduce postoperative VAS scores of parturient women effectively, improve postoperative comfort of parturient women;and it is safe and reliable.