| 肝癌新的血清标记物高尔基体蛋白73 |
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| 引用本文： | 巢映晖,傅华群.肝癌新的血清标记物高尔基体蛋白73[J].中华肝胆外科杂志,2011,17(12). |
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| 作者姓名： | 巢映晖 傅华群 |
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| 作者单位： | 330006, 南昌大学第二附属医院肝胆外科 |
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| 摘 要： | 高尔基体蛋白73(GP73)是细胞高尔基体上的一种Ⅱ型跨膜蛋白.近期越来越多的研究证明,GP73表达与原发性肝癌(PHC)关系密切,其敏感性和特异性均超过了甲胎蛋白(AFP),有可能成为诊断PHC,尤其是早期PHC新的血清标志物.文章对GP73与肝癌的关系做一综述.
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| 关 键 词： | 高尔基体蛋白 肿瘤标记物 原发性肝癌 诊断 |
Golgiprotein-73, a novel serum marker for primary hepatocar cinoma |
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| CHAO Ying-hui,FU Hua-qun.Golgiprotein-73, a novel serum marker for primary hepatocar cinoma[J].Chinese Journal of Hepatobiliary Surgery,2011,17(12). |
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| Authors: | CHAO Ying-hui FU Hua-qun |
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| Abstract: | Golgi protein-73 (GP73) is a type-lⅡ Golgi glycoprotein localized on the membrane of the Golgi complex.Recently,a growing number of studies have demonstrated that the expression of GP73 is closely correlated with primary hepatocarcinoma (PHC).GP73 has a higher sensitivity and specificity than alpha-fetoprotein (AFP) and it may be a novel serum marker for the detection of PHC,especially for early PHC.This article reviews the relationship between GP73 and PHC. |
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| Keywords: | Golgi protein-73 Tumor marker Primary hepatocarcinoma Diagnosis |
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