帕金森病发病的相关危险因素分析

目的探讨帕金森病（PD）发病的危险因素,为PD的预防和治疗提供参考。方法对120例PD患者的临床资料进行回顾性分析,对PD发病的相关危险因素进行Logistic回归分析,筛选PD发病的相关危险因素。结果单因素分析结果显示,饮酒、吸烟、饮茶、脑力劳动、杀虫剂接触史与PD发病有关,而PD发病与文化程度、高血压病史、2型糖尿病、阳性家族史等无明显相关性（P〉0.05）;多因素Logistic回归法分析表明,无饮茶史、有杀虫剂接触史和无吸烟史是PD发病的危险因素。结论无饮茶史、有杀虫剂接触史和无吸烟史是PD发病的危险因素,对这些危险因素加以重点评估和合理控制,可以预防PD的发生。

Study on risk factors of incidence of parkinson's disease

Objective To investigate the risk factors of incidence of parkinson＇s disease （PD）, and provide reference for prevention and treatment of PD incidence. Methods 120 cases of PD patients were studied, analyzing and screening the risk factors of PD incidence by Logistic. Results The single-factor analysis showed that drinking, smoking, tea, mental, and history of exposure to pesticides had certain degree of contact with PD incidence. The education level, history of hypertension, type 2 diabetes and positive family history was no significant correlation with the PD incidence. Multivariate Logistic regression analysis showed that no tea＇s history, history of exposure to pesticides and no smoking history were risk factors of PD incidence. Conclusion The no tears history, history of exposure to pesticides and no smoking history are the risk factors of PD incidence, assessment and control these risk factors can reduce PD incidence.