卒中后抑郁与脑小血管病关系的研究进展

卒中后抑郁为卒中常见并发症之一，不仅影响患者的精神及神经功能恢复，甚至增加患者的病死率、致残率，对患者的预后产生消极影响。卒中后抑郁与病变部位、病变程度等存在一定程度的相关性，但近年来研究证实脑小血管病变同样与卒中后抑郁的发生密切相关，随着人口老龄化的加剧，脑小血管病的发病率随之增加，它不仅是卒中后抑郁发生的危险因素，并且会加重卒中后抑郁的严重程度。本文对脑小血管病与卒中后抑郁的关系做一综述。

Research Progress of Post-stroke Depression and Cerebral Small Vessel Diseases

The post-stroke depression (PSD) is one of the common complications after stroke. It not only affects the recovery of the psychiatric and neurological function in patients, but also increases mortality and morbidity, resulting in a negative influence for the prognosis in patients with stroke. There is a certain degree of correlation between the PSD and the lesion site, degree of pathological changes. But recent studies demonstrated that the cerebral small vessel diseases (CSVD) are also closely related to the occurrence of PSD. With the increasing of the aging population, the occurrence of the CSVD is raising. The CSVD is not only an important risk factor of PSD, but also increases the severity of PSD. In this article, we made a review of the relationship between CSVD and PSD.