2004-2010年某部食品和公共场所从业人员乙肝病毒感染状况分析

目的]掌握某部食品、公共场所从业人员HBV感染情况及其动态变化，为开展乙肝防治工作提供依据。方法]对2004～2010年在某部防疫队体检的解放军某部食品和公共场所从业人员血清HBV感染标志物检测资料进行分析。结果32004-2010年累计检测某部食品和公共场所从业人员19008名，检出HBV感染者7569人，年均感染率为39．82％，各年感染率分别为52．81％、52．66％、45．76％、42．95％、28．73％、28．25％、27．62％（P〈0．01）。HBsAg、抗-HBs、HBeAg、抗-HBe、抗HBc年均阳性率分别为5．12％、35．23％、2．08％、5．96％、6．01％。HBV年均感染率，男性、女性分别为45．88％、28．58％，农村籍、城镇籍的分别为43．47％、25．10％，公共场所、食品从业人员分别为45．92％、21．02％，有、无乙肝疫苗接种史者分别为12．36％、53．55％，差异均有统计学意义（P〈0．01）；HBV感染率随着年龄的增长而降低（P〈0．01）；12672名无乙肝疫苗接种史者中，单纯HBsAg阳性的占6．91％，单纯HBeAg阳性的占2．71％，单纯抗-HBe阳性的占7．40％，单纯抗HBc阳性者占6．64％，抗-HBe、抗-HBc阳性的占4．60％，“小三阳”占2．51％，“大三阳”占2．11％。结论]某部食品和公共场所从业人员HBV感染状况不严重。

Analysis of the Infection of Hepatitis B Virus among Employees in Food and Public Places, 2004-2010

Objective]To understand the status of HBV infection and the prevalence among employees in food and pub- lic places in the army,to provide the basis for prevention and control of hepatitis B. Methods]Examination data of serum markers of HBV infection tested for the employees of food and public places in the army from 2004 to 2010 were analyzed. Results]Altogether 19 008 employees in food and public places in the army were tested from 2004-2010,7 569 employees were infected with HBV,the annual infection rate was 39.82%,the annual infection rate was 52.81%,52.66 %,45.76%, 42.95%,28.73%,28.25% and 27.62% respectively each year （P 〈0.01）.The annual positive rate of HBsAg,anti HBs, HBeAg,anti HBe,anti-HBc was 5. 12%,35.23% ,2.08% ,5.96% and 6.01% respectively. The annual infection rate of HBV was 45.88% and 28.58% in male and female,as well as 43.47N and 25.10% in the employees from rural area and town respectively. It was 45.92% and 21.02% in the employees in public and food places. 12.36% of them had the history of vaccination but 53.55 % of them had not been vaccinated, there was a difference （ P 〈0.01）. HBV infection rate declined with the increase of age （ P d0.01）. Of the 12 672 employees who had not been vaccinated,the only positive rate of HBsAg,HBeAg,anti HBe,anti HBc,anti-HBe and anti-HBc accounted for 6.91%,2.71% ,7.40%,6.64% and 4.60% respectively. The positive rate of HBsAg,HBeAb and HBcAb （small 3 this world） was 2.51% ,well the positive rate of HBsAg,HBeAg and HBeAb （big 3 this world） was 2.11%. Conclusion]The infection status of HBV among the employees in food and public places in the army was not serious.