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Hepatitis B and C virus infections in Turkish children with haemophilia
Authors:E KocabasL  N Aksaray  E Alhan  F Yarkin  F Köksal  Y Kilinç
Institution:Department of Paediatric Infection, Çukurova University, Faculty of Medicine, Adana, Turkey;Department of Haematology, Çukurova University, Faculty of Medicine, Adana, Turkey;Department of Microbiology, Çukurova University, Faculty of Medicine, Adana, Turkey
Abstract:We examined 41 Turkish children with haemophilia for evidence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections using the enzyme-linked immunosorbent assay (ELISA). Hepatitis B surface antigen was found to be positive in 11 patients (26. 8%) and HCV-specific antibody (anti-HCV) was detected in 10 (24. 4%) patients. There was a close relationship of the number of transfusions of blood plasma to the presence of HCV specific antibody, but not to the serum markers of HBV infection. In countries where HBV infection is commonly seen and problems in transfusion practice continue, as in Turkey, children with haemophilia are at greater risk for HBV and HCV infections.
Keywords:Haemophilia  hepatitis B  hepatitis C
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