| 人参皂甙对淹溺防治的实验研究 |
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| 引用本文： | 白亚夫,孟丽娟.人参皂甙对淹溺防治的实验研究[J].河南医学研究,1994,3(1):46-49. |
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| 作者姓名： | 白亚夫 孟丽娟 |
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| 作者单位： | 洛阳医学高等专科学校病理生理学教研室 |
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| 摘 要： | 用家兔作动物模型，研究了人参茎叶皂甙对淹溺机体的防治作用。防治组于实验前２４ｈ及１５ｍｉｎ经腹腔给予人参皂甙（２０．１３ｍｇ／ｍｌ，２ｍｌ／ｋｇ），结果表明，人参皂甙可保护脂质过氧化物对心、脑、肺的损害，增加短期（２ｈ）存活率，显著提高动脉血氧分压（ＰａＯ２）、血氧饱和度（ＳａｔＯ２）并降低二氧化碳分压（ＰａＣＯ２）、肺泡氧与动脉血氧分压差（ＰＡ－ａＤＯ２），与对照组比较，能明显减轻防治组肺水肿。
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| 关 键 词： | 人参皂甙，淹溺，丙二醛 |
THE PREVENTIVE AND CURATIVE EFFECTS OF GINSENOSIDE ON DROWNING IN RABBITS |
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| Bai Ya-fu et al.THE PREVENTIVE AND CURATIVE EFFECTS OF GINSENOSIDE ON DROWNING IN RABBITS[J].Henan Medical Research,1994,3(1):46-49. |
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| Authors: | Bai Ya-fu |
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| Abstract: | The effects of Ginseoside(GS)from stems and leaves on experimentaldrowning was studied in a rabbit model,GS(20. 13mg/ml,2ml/kg)was given via peritonealcavity 24 h and 15 min before experiment in treatment group.The results indicated that GS had cause protective activity on lipid peroxide in injuredthe brain,heart,lungs and significantly increased short term(i,e,2 h)survival rate,elevatedPaO2,SatO2,and fell PaCO2,PA-aDO2.The pulmonary edema was reduced significantly in the animal of treatmental group thancontrol group. |
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| Keywords: | ginsenoside drowning malondialdehyde(MDA ) |
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