米非司酮配伍米索前列醇和结合雌激素软膏应用于绝经后妇女取环术中的效果观察

目的：探讨绝经后妇女节育环取出的方法,比较米非司酮配伍米索前列醇、阴道塞用结合雌激素软膏用于绝经后节育环取环的效果。方法：回顾性分析本院近7年来绝经后要求取出节育环的妇女,共87例,分为三组,甲组32例,口服米非司酮50mg,2次/d,共2d,第3天用米索前列醇400μg塞阴道;乙组30例,阴道涂敷结合雌激素软膏2g,1次/d,共10d;对照组25例,术前无处理。比较三组取环时情况及手术成功率。结果：甲组宫颈扩张情况、手术时间、术中出血量、手术成功率、术后腹痛持续时间与其他两组相比,差异有统计学意义（P〈0.05）。乙组与对照组相比,宫颈扩张情况、手术成功率差异有统计学意义（P〈0.05）,而手术时间、术中出血量、术后腹痛持续时间无差异无统计学意义（P〉0.05）。结论：米非司酮配伍米索前列醇用于绝经后节育环取环安全、有效、成功率高、副作用小,值得推广。阴道涂敷结合雌激素软膏在绝经后节育环取环上也有一定疗效。

Effect of Observation on Mifepristone Combined with Misoprostol and Premarin Ointment Applied to the Postmenopause Ring Intraoperative

Objective：To explore the postmenopausal women out of the coil method,compare the effect of compatibility misoprostol,mifepristone vagina with premarin ointment used for postmenopause ring intraoperative.Method：A total of 87 cases for postmenopause ring intraoperative nearly 7 years were analyzed retrospectively,they were divided into three groups,the group A was 32 cases,oral mifepristone 50 mg twice a day,a total of 2 d,3 days from rice suo forefront alcohol 400 μg plug vagina;the group B was 32 cases,vaginal coating,combined with the premarin ointment 2 g,once a day, a total of 10 d,the control group was 25 cases,preoperative without processing. The situation and success rate of surgery when you pick up the ring was compared among the three groups.Result：The cervical dilation,operative time,intraoperative blood loss,surgical success rate,duration of postoperative abdominal pain in group A compared with other two groups,had the significant difference（P ＆lt;0.05）. The group B was compared with the controu group, had the significant difference（P ＆lt;0.05）,but the operation time,intraoperative blood loss,duration of postoperative abdominal pain had no difference （P ＆gt;0.05）.Conclusion：Mifepristone combined with misoprostol for postmenopause ring intraoperative is safe,effective and high success rate,small side effects,it is worthy of promotion. Coating premarin ointment in postmenopause ring intraoperative also have certain curative effect.