维吾尔族与汉族巨脑回畸形伴发病的对比分析

目的：探讨维吾尔族与汉族患者巨脑回畸形伴发病变的类型是否一致。方法：收集本院2004-2012年16例维吾尔族巨脑回畸形患者的MRI影像资料,回顾性分析其伴发病变类型,通过所得资料与汉族患者文献资料数据进行对比分析。结果：维吾尔族16例患者中4例伴发交通性脑积水,3例伴发脑裂畸形,3例伴发脑白质营养不良,2例伴发Dandy-Walker畸形,1例伴发胼胝体发育不全、透明隔缺如,1例伴发有灰质移位,3例伴发蛛网膜囊肿,6例未见明确伴发畸形。结论：维吾尔族与汉族患者巨脑回畸形伴发病变的类型是不一致的,灰质异位,汉族患者文献报道可达50%,而维吾尔族患者仅占6%;16例维吾尔族巨脑回患者中伴发脑白质营养不良3例,伴发蛛网膜囊肿者3例,其他文献未见报道。

Comparative Analyses of Pachygyria Concomitant Lesions between Uyghur and Han Nationality

Objective：To evaluate whether the type of pachygyria concomitant lesions between Uyghur and Han patients is consistent.Method： From 2004-2012 year,Collected MRI image data of 16 Uygur pachygyria deformity patients,retrospectively analysed the type of concomitant lesions and comparison with the Han concomitant patients.Result：Four in Uygur 16 patients were associated with communicating hydrocephalus;three were associated with leukodystrophies;two were associated with Dandy-Walker malformation;One was associated with corpus callosum hypoplasia absence of the septum pellucidum;One was associated with gray matter shift;Three were associated with arachnoid cyst;six were not clearly associated malformations.Conclusion：The type of pachygyria concomitant lesions between Uyghur and Han patients is inconsistent.As for heterotopic gray matter,Han patients are reported in the literature up to 50%,while only 6% for Uyghur patients;Among 16 cases of pachygyria concomitant lesions,there are three cases with leukodystrophies,and three with arachnoid cysts,and no other documents are reported.