肺心病合并脑梗死患者血液流变及血气分析

目的：探讨肺心病合并脑梗死患者的血液流变和动脉血气的改变。方法：选取近期来本院就诊的肺心病患者58例,脑梗死患者62例,肺心病合并脑梗死患者48例,同时,另选50例健康老年人作为健康对照组。对所有患者进行全血粘度、血浆粘度、血沉、红细胞压积和纤维蛋白原检测,并计算红细胞聚集指数等血流变指标。测定氧分压、二氧化碳分压、第一秒用力呼气容积等肺功能指标,比较各组患者各指标的差异。结果：肺心病合并脑梗死组患者血流变各指标明显高于对照组、脑梗死组和肺心病组（P〈0.01）;肺心病合并脑梗死组患者的PaO2、FEV1明显低于对照组、脑梗死组和肺心病组（P〈0.01）,而肺心病合并脑梗死组患者的PaCO2均高于其他三组（P〈0.01）。结论：肺心病和脑梗死对正常血液流变及肺功能的损害存在交互作用,血液流变和动脉血气检测对肺心病合并脑梗死的诊断及治疗有一定的指导意义。

Blood Rheology and Blood Gas Analysis Effect in Patients with Cor Pulmonale Combination Cerebral Infarction

Objective：To study arterial blood gas and blood rheology in patients with cor pulmonale combination cerebral infarction.Method： 58 patients who suffered Cor Pulmonale,62 patients who suffered cerebral infarction and 48 patients with cor pulmonale combination cerebral infarction were selected.50 healthy old people were selected as a healthy control group at the same time.For all patients with whole blood viscosity,plasma viscosity,blood sedimentation,red blood cells deposited and fibrinogen detection,indexes such as red blood cell aggregation index were all calculated.Determination of oxygen partial pressure,CO2 partial pressure,the first second forced expiratory volume,which were the indices of pulmonary function to compare the difference between the groups of patients with various indicators.Result：The indexes of blood rheology in cor pulmonale combination cerebral infarction patients group was obviously higher than that of control group,the cerebral infarction group and cor pulmonale group（P〈0.01）;the PaO2 and FEV1 in cor pulmonale combination cerebral infarction patients group was obviously lower than the control group,the cerebral infarction group and cor pulmonale group（P〈0.01）;and the PaCO2 in cor pulmonale combination cerebral infarction patients group was higher than the other three groups（P〈0.01）.Conclusion：The damage of cor pulmonale and cerebral infarction to the blood rheology and lung function exist interaction,blood rheology and arterial blood gas test of cor pulmonale combination cerebral infarction has certain guiding significance to both diagnosis and treatment.