Successful transcatheter arterial antimicrobial and steroid therapy for refractory liver abscess in chronic granulomatous disease: A case report and review of literature |
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Authors: | Taito Kitano Yuki Nishikawa Satoru Sueyoshi Noriko Horikawa Hiroyuki Nakagawa Sayaka Yoshida |
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Affiliation: | 1. Nara Prefecture General Medical Center, Department of Pediatrics, Nara, Japan;2. Johns Hopkins Bloomberg School of Public Health, Master of Public Health Program, Baltimore, MD, USA;3. Nara Medical University, Department of Pediatrics, Kashihara, Japan;4. Nara Prefecture General Medical Center, Department of Radiology, Nara, Japan |
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Abstract: | Hepatic abscess in chronic granulomatous disease (CGD) is very refractory and frequently requires multiple surgeries with frequent morbidities. Although surgical interventions are often required, patients are often not able to have surgery for various reasons. We present the case of a 21-year-old man with recurrent hepatic abscess in CGD. We could not provide surgical interventions due to the lack of a fluid cavity and the patient's refusal, and therefore we administered transcatheter arterial antimicrobial and steroid therapy. He did not have any exacerbation for more than 18 months after the final transcatheter treatment. This is the first reported case of successful transcatheter arterial antimicrobial and steroid therapy for refractory hepatic abscess in CGD. Although the patient's burden and medical cost were not inconsequential, this case shows that the transcatheter arterial antimicrobial and steroid therapy may be a treatment option for patients who are not candidates for surgical interventions. |
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Keywords: | Chronic granulomatous disease Liver abscess Transcatheter arterial therapy |
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