| 药物制剂非溶剂包衣工艺的研究进展 |
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| 引用本文： | 颜圣,刘晓旭.药物制剂非溶剂包衣工艺的研究进展[J].药学服务与研究,2009,9(2):84-87. |
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| 作者姓名： | 颜圣 刘晓旭 |
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| 作者单位： | 1. 广州中一药业有限公司产品开发部,广州,510140
2. 中国药科大学药学院药剂学教研室,南京,210009 |
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| 基金项目： | 广东省技术创新项目资助项目 |
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| 摘 要： | 综述国外近年来报道的非溶剂包衣法在药剂学领域的研究进展。介绍几种具代表性的非溶剂包衣方法,包括干粉包衣、热融包衣、静电包衣、压制包衣、光熟化包衣和超临界流体包衣等,及其在速释和缓控释制剂中的应用,为设计更加安全、便利和高效的包衣方法提供理论依据和商业参考。
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| 关 键 词： | 非溶剂包衣 药剂学 口服固体制剂 释药方式 综述 |
Advances in research on pharmaceutics of solventless coating |
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| YAN Sheng,LIU Xiao-xu.Advances in research on pharmaceutics of solventless coating[J].Pharmaceutical Care and Research,2009,9(2):84-87. |
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| Authors: | YAN Sheng LIU Xiao-xu |
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| Institution: | 1. Department of Product Development, Guangzhou Zhongyi Pharmaceutical Limited Company, Guangzhou 510140, China; 2. Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China) |
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| Abstract: | The research progress on solventless coating in pharmaceutics is reviewed in this paper. Several representative solventless coating methods, including dry powder coating, hot-melt coating, electrostatic coating, compression coating, photocurable coating, supereritical fluid coating etc, and their application in quick and sustained release preparations are introduced for the purpose of providing theoretical basis and commercial reference for designing safer, more convenient and efficient coating methods. |
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| Keywords: | solventless coating pharmaceutics oral solid dosage forms drug delivery system review |
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